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The balance between cathepsin C and cystatin F controls remyelination in the brain of Plp1-overexpressing mouse, a chronic demyelinating disease model.

Glia. 2017 Jun;65(6):917-930. doi:10.1002/glia.23134. Epub 2017 Mar 02
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摘要


transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.

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基因功能


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原始数据


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