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13011 Cst7

13011

Cst7

cystatin F (leukocystatin)

protein-coding

Mus musculus

基因描述

Type Description
Definition cystatin F (leukocystatin)

研究结论

Date Results Publications
2019-11-02 12:30:00 These results indicate that hypoxia BV2 cells highly express Cystatin F, which is involved in A2A R activation-mediated neuroinflammation via the and or ERK1/2 signaling pathways. 29717153
2018-06-30 10:24:00 High CST7 expression is associated with Alzheimer's disease. 28904096
2017-08-19 10:05:00 Our results validate cystatin F as a useful biomarker of early pathogenesis in experimental models of prion disease, and point to unexpected species-specific differences in the transcriptional responses to prion infections. 28178353
2017-05-07 00:47:00 During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process. 28251676
2013-06-15 11:00:00 The cystatin F expression in the activated microglia is closely associated with the effect of the A2A receptors, which may be related to the neuroinflammatory responses occurring during the pathological process. 23285090

名称对应

Type IDs
Synonymous Cmap
Gene
UniProtKB-ID: CYTF_MOUSE, Q9QWL5_MOUSE
UniprotKB: O89098, Q9QWL5
UniParc: UPI00000297D9, UPI0000022BDD
EMBL: AB015224, AF031825, BC117049, BC117047, AK004420, AF031826
Ensembl: ENSMUSG00000068129
KO: mmu:13011
Nucleutide sequences
EMBL-CDS: AAC40139.1, AAC40140.1, AAI17050.1, BAA34940.1, BAB23298.1, AAI17048.1
Ensembl_TRS: ENSMUST00000089200
Protein sequencees
Ensembl_PRO: ENSMUSP00000086606
RefSeq: NP_034107.2
Others
UniRef100: UniRef100_O89098
UniRef90: UniRef90_O89098
UniRef50: UniRef50_O76096
UniGene: Mm.12965
CCDS: CCDS16857.2

全选

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