| Type | Description |
|---|---|
| Definition | neuraminidase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:06:00 | Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells. | 30700826 |
| 2017-06-03 10:15:00 | The most potent compound tested targeted the human Neu4 isoenzyme, and was able to substantially reduce the rate of cell migration. We found that the lateral mobility of integrins was reduced by treatment of cells with Neu3, suggesting that Neu3 enzyme activity resulted in changes to integrin-co-receptor or integrin-cytoskeleton interactions | 27344026 |
| 2016-03-12 11:42:00 | The silencing or chemical inhibition of NEU4 changes the entire glycosylation pattern of proteins and lipids, making it more similar to that of differentiated GBM cells and drastically reduces GSCs survival. | 25144716 |
| 2014-12-20 11:55:00 | The results demonstrate that the proline-rich region can also enhance cell proliferation and retinoic acid (RA)-induced neuronal differentiation and it is also involved in NEU4 interaction with Akt. | 24030392 |
| 2012-11-03 10:12:00 | Overexpression of NEU4 is associated with neuroblastoma. | 22287118 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
NEUR4_HUMAN,
Q3KR05_HUMAN,
B3KR54_HUMAN
UniprotKB:
Q8WWR8,
Q3KR05,
B3KR54
UniParc:
UPI000013DD9B,
UPI0000EE378E,
UPI000004FAD3,
UPI00005C92F9
EMBL:
AK300969,
AY203952,
CH471063,
AK289421,
BC105974,
AJ277883,
AC114730,
BC012899,
AK091038,
BC117214
Ensembl:
ENSG00000277926,
ENSG00000204099
KO:
hsa:129807
|
| Nucleutide sequences |
EMBL-CDS:
AAX82022.1,
CAC81904.1,
BAF82110.1,
AAH12899.2,
EAW71296.1,
AAP34475.1,
AAI05975.1,
AAI17215.1,
EAW71295.1,
BAG52266.1,
BAH13385.1
Gene_ORFName:
LP5125,
hCG_31619
Ensembl_TRS:
ENST00000616490,
ENST00000325935,
ENST00000405370,
ENST00000630923,
ENST00000626600,
ENST00000407683,
ENST00000618866,
ENST00000621851,
ENST00000404257,
ENST00000391969
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384804,
ENSP00000485701,
ENSP00000375830,
ENSP00000483726,
ENSP00000385402,
ENSP00000486602,
ENSP00000482722,
ENSP00000320318,
ENSP00000478409,
ENSP00000385149
RefSeq:
NP_001161071.1,
NP_542779.2,
NP_001161072.1,
NP_001161073.1,
NP_001161074.1
|
| Others |
UniRef100:
UniRef100_Q8WWR8,
UniRef100_Q3KR05
UniRef90:
UniRef90_Q8WWR8
UniRef50:
UniRef50_Q8WWR8
UniGene:
Hs.551747
CCDS:
CCDS2553.1,
CCDS54442.1,
CCDS54441.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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