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12873 Cpa3

12873

Cpa3

carboxypeptidase A3, mast cell

protein-coding

Mus musculus

基因描述

Type Description
Definition carboxypeptidase A3, mast cell

研究结论

Date Results Publications
2017-09-09 11:03:00 The goal of the current study was to compare bone repair in normal wild type and Cpa3Cre/+ mice, which lack mast cells in the absence of any other hematopoietic or non- hematopoietic deficiencies. Mast cells appear in healing bone of wild type mice but not Cpa3Cre/+ mice, beginning 14 days after surgery. Re-vascularization of repair tissue and deposition of mineralized bone was delayed and dis-organised in Cpa3Cre/+ mice 28350850
2017-06-24 11:39:00 Mast cells in experimental arthritis contained high levels of mMC-CPA mRNA, and also lacked the exopeptidase. 28193842
2012-03-24 11:47:00 Data suggest that carboxypeptidase A3 (Cpa3)-Cre; myeloid cell leukemia sequence 1 (Mcl-1)(fl/fl) mice may be useful in analyzing the roles of mast cells and basophils in health and disease. 22001390
2010-01-21 00:00:00 Mc-cpa plays a crucial role for the generation of phenotypically mature mast cells. 15988029
2010-01-21 00:00:00 cathepsin E is located in mast-cell secretory granules in complex with heparin proteoglycans, and has a role in the processing of procarboxypeptidase A into active protease 15860733

名称对应

Type IDs
Synonymous MC-CPA
Gene
UniProtKB-ID: CBPA3_MOUSE, Q542E3_MOUSE
UniprotKB: P15089, Q542E3
UniParc: UPI00000041BD
EMBL: AK088906, J05118
Ensembl: ENSMUSG00000001865
KO: mmu:12873
Nucleutide sequences
EMBL-CDS: AAA37369.1, BAC40646.1
Ensembl_TRS: ENSMUST00000001921
Protein sequencees
Ensembl_PRO: ENSMUSP00000001921
RefSeq: XP_006535445.1, NP_031779.1
Others
UniRef100: UniRef100_P15089
UniRef90: UniRef90_P15089
UniRef50: UniRef50_P15089
UniGene: Mm.1135
CCDS: CCDS17262.1

全选

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研究热度

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