| Type | Description |
|---|---|
| Definition | catechol-O-methyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:20:00 | desmocollin-1 (DSC1) is validated as a protein connected with lymph node status of luminal A breast cancer, tumor grade, and Her-2 status and catechol-O-methyltransferase is successfully verified as a protein associated with lymph node metastasis of triple negative breast cancer. | 31617665 |
| 2019-03-02 12:13:00 | These results suggest that COMT is an enzyme to maintain glucose homeostasis and 2-methoxyestradiol is a potential endogenous multi-target anti-diabetic candidate. | 28801594 |
| 2017-05-13 20:23:00 | Miroestrol restored uterine COMT expression in beta-naphthoflavone-treated mice. | 26893163 |
| 2016-05-07 12:20:00 | This study report that genetically driven reduction in COMT enzyme activity increased cortical thickness in the prefrontal cortex (PFC) and postero-parieto-temporal cortex of male, but not female adult mice. | 24658585 |
| 2015-11-14 10:31:00 | COMT expression in the hippocampus was significantly reduced by high E2 replacement, implying increased catecholamine levels in the hippocampus of high E2 mice. | 25555360 |
| Type | IDs |
|---|---|
| Synonymous | Comt1, D16Wsu103e, D330014B15Rik |
| Gene |
UniProtKB-ID:
COMT_MOUSE
UniprotKB:
O88587
UniParc:
UPI0000020A87,
UPI00027DB795
EMBL:
AK148311,
AC133487,
BC010402,
AF076156
Ensembl:
ENSMUSG00000000326,
ENSMUSG00000098892
KO:
mmu:12846
|
| Nucleutide sequences |
EMBL-CDS:
AAH10402.1,
AAC33334.1,
BAE28473.1
Ensembl_TRS:
ENSMUST00000195169,
ENSMUST00000183626,
ENSMUST00000000335,
ENSMUST00000165430,
ENSMUST00000185030,
ENSMUST00000115609
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000000335,
ENSMUSP00000130077,
ENSMUSP00000111272,
ENSMUSP00000138930,
ENSMUSP00000141683,
ENSMUSP00000139196
RefSeq:
NP_001104532.1,
NP_031770.2,
XP_036015657.1,
NP_001104533.1
|
| Others |
UniRef100:
UniRef100_O88587
UniRef90:
UniRef90_P22734
UniRef50:
UniRef50_P21964
UniGene:
Mm.100940
CCDS:
CCDS28021.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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