Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity.
Neuropsychopharmacology. 2016 Dec;41(13):3060-3069. Epub 2016 Jul 08
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摘要
Met polymorphism, and suggest that COMT's effects are most prominent when the dopamine system is challenged. Finally, they demonstrate the importance of considering COMT genotype when examining the therapeutic potential of COMT inhibitors.
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基因功能
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原始数据
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文献解读
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