| Type | Description |
|---|---|
| Definition | cyclin-dependent kinase 7 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:40:00 | the cyclin-dependent kinase CDK7 is regulated by miR-210 and is necessary for normal NP cell-cycle progression. Our findings demonstrate that miRNAs are essential for normal NP proliferation and cell-cycle progress during neocortical development | 27411104 |
| 2017-10-07 10:20:00 | Inhibition of CDK7 bypasses spindle assembly checkpoint via premature cyclin B degradation during oocyte meiosis. | 27693251 |
| 2012-08-18 10:18:00 | Whereas Cdk7 was completely dispensable for global transcription, it was essential for the cell cycle via phosphorylation of Cdk1 and Cdk2. In vivo, Cdk7 was indispensable for cell proliferation except during the first stages of embryonic development. | 22505032 |
| 2010-06-28 11:58:00 | investigated the function of the Cdk7.cyclin H.Mat1 complex in murine embryonic stem (ES) cells and preimplantation embryos to determine whether it regulates the unique cell cycle structure and transcriptional network of pluripotent cells | 20231280 |
| 2010-01-21 00:00:00 | Cdk7 kinase activity and cell cycle kinetics were found to be comparable in wild-type and Hint(-/-) mouse embryonic fibroblasts, suggesting that Hint may not be a key regulator of Cdk7 activity | 12748294 |
| Type | IDs |
|---|---|
| Synonymous | AI323415, AI528512, C230069N13, Cdkn7, Crk4 |
| Gene |
UniProtKB-ID:
CDK7_MOUSE,
Q3THG5_MOUSE
UniprotKB:
Q03147,
Q3THG5
UniParc:
UPI0000021C7E
EMBL:
X74145,
BC068160,
AK168286,
BC004605,
AK145759,
U11822,
BC141043,
X65070,
X57239
Ensembl:
ENSMUSG00000069089
KO:
mmu:12572
|
| Nucleutide sequences |
EMBL-CDS:
AAH68160.1,
AAA64831.1,
CAA52242.1,
CAA46203.1,
CAA40515.1,
AAH04605.1,
AAI41044.1,
BAE40231.1,
BAE26631.1
Ensembl_TRS:
ENSMUST00000091299
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000088845
RefSeq:
NP_034004.2
|
| Others |
UniRef100:
UniRef100_Q03147
UniRef90:
UniRef90_P51952
UniRef50:
UniRef50_P50613
UniGene:
Mm.259718
CCDS:
CCDS36766.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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