| Type | Description |
|---|---|
| Definition | serine (or cysteine) peptidase inhibitor, clade G, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-18 10:32:00 | C1INH has an important role as a gatekeeper to the brain via the neurovascular system. | 30882931 |
| 2013-06-01 11:23:00 | C1INH prevented myocardial ischemia reperfusion injury in mice. | 22705194 |
| 2010-01-21 00:00:00 | Transgenic mice have been generated that express human C1 inhibitor mRNA and protein under the control of the human promoter and regulatory elements; C1nh production is demonstrated in mouse brain, spleen, liver, heart, kidney, and lung. | 12421980 |
| 2010-01-21 00:00:00 | In vivo, C1 inhibitor (C1INH) reduces the number of viable bacteria in the blood and peritoneal fluid and accelerates killing of bacteria by blood neutrophils and peritoneal macrophages. | 17785834 |
| 2010-01-21 00:00:00 | C1-inhibitor limits neointimal plaque formation and inflammation. This may involve blockade of complement activation, inhibition of leukocyte recruitment, and reduced triglyceride levels | 18071075 |
| Type | IDs |
|---|---|
| Synonymous | C1INH, C1nh |
| Gene |
UniProtKB-ID:
IC1_MOUSE
UniprotKB:
P97290
UniParc:
UPI0000022106
EMBL:
AL928914,
AF010254,
BC002026,
Y10386,
AF052039
Ensembl:
ENSMUSG00000023224
KO:
mmu:12258
|
| Nucleutide sequences |
EMBL-CDS:
CAA71412.1,
AAC40149.1,
AAH02026.1,
AAC40136.1
Ensembl_TRS:
ENSMUST00000023994
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023994
RefSeq:
NP_033906.2,
XP_006498686.1
|
| Others |
UniRef100:
UniRef100_P97290
UniRef90:
UniRef90_P97290
UniRef50:
UniRef50_P97290
UniGene:
Mm.38888
CCDS:
CCDS16193.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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