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121642 ALKBH2

121642

ALKBH2

alkB homolog 2, alpha-ketoglutarate dependent dioxygenase

protein-coding

Homo sapiens

基因描述

Type Description
Definition alkB homolog 2, alpha-ketoglutarate dependent dioxygenase

研究结论

Date Results Publications
2021-04-03 13:34:00 Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB. 33161373
2019-11-30 10:54:00 Data show that the three DNA repair enzymes ALKBH2, ALKBH3, and AlkB are not only able to repair DNA adducts, but also can edit the epigenetic modification and generate the corresponding oxidative derivatives. 31114894
2017-04-08 10:24:00 These results revealed that N3-ethylthymidine , but not other DNA lesions, could be repaired by Alkbh2 and Alkbh3 in mammalian cells. 26930515
2016-06-28 11:16:00 studies reveal the ALKBH2 binding interface of PCNA and indicate that both germline and somatic ALKBH2 variants could have cellular effects on ALKBH2 function in DNA repair. 26408825
2015-09-05 10:48:00 It was shown for first time that DNA glycosylase ALKBH2 can repair DNA adduct 1,N2-ethenoguanine. 25797601

名称对应

Type IDs
Synonymous ABH2
Gene
UniProtKB-ID: ALKB2_HUMAN
UniprotKB: Q6NS38
UniParc: UPI0000160F58, UPI0000488795
EMBL: BC070489, AB277859, AC011596, AY754389
Ensembl: ENSG00000189046
KO: hsa:121642
Nucleutide sequences
EMBL-CDS: AAH70489.1, AAV28301.1, BAF56576.1
Ensembl_TRS: ENST00000440112, ENST00000343075, ENST00000619381, ENST00000429722
Protein sequencees
Ensembl_PRO: ENSP00000343021, ENSP00000478765, ENSP00000399820, ENSP00000398181
RefSeq: NP_001001655.1, XP_005253892.1, NP_001192108.1, NP_001138847.1, NP_001138846.1, XP_005253893.1, NP_001192109.1
Others
UniRef100: UniRef100_Q6NS38
UniRef90: UniRef90_Q6NS38
UniRef50: UniRef50_Q6NS38
UniGene: Hs.374458
CCDS: CCDS55883.1, CCDS31897.1

全选

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