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11818 Apoh

11818

Apoh

apolipoprotein H

protein-coding

Mus musculus

基因描述

Type Description
Definition apolipoprotein H

研究结论

Date Results Publications
2020-04-18 11:07:00 self-antigen (i.e. beta2 GPI) presented in the context of necroptosis and proinflammatory signals may be sufficient to overcome immune tolerance and induce Systemic lupus erythematosus. 31187539
2018-04-21 10:54:00 During the parasite's hepatic replication, the C-terminal region of EXP-1 binds ApoH. This molecular interaction plays a pivotal role for successful Plasmodium liver-stage development. Down-regulation of ApoH expression in either hepatic cells or mouse livers by RNA interference resulted in impaired intrahepatic development. 28137845
2018-01-13 14:22:00 A1-A1, which is a soluble analog of ApoER2 that binds pathological beta2GPI/anti-beta2GPI complexes, has a positive impact on hemodynamics in lupus-prone mice with spontaneous anti-beta2GPI antibodies and hypertension 26990752
2017-04-22 11:31:00 These results suggested that CRP/oxidized low density lipoprotein/beta 2-Glycoprotein I complexes may induce lipid accumulation and inflammation in macrophages via the p38/MAPK and NFkappaB signaling pathways. 27512978
2016-09-24 12:01:00 TLR2 increase the stimulating effect of beta2GP1/anti-beta2GP1 complex on the expression of TNF-alpha in mouse peritoneal macrophages 27053607

名称对应

Type IDs
Synonymous B2GPI, beta-2-GPI, beta2-GPI
Gene
UniProtKB-ID: APOH_MOUSE, Q9CY42_MOUSE
UniprotKB: Q01339, Q9CY42
UniParc: UPI0000001992, UPI00000E5913
EMBL: Y11356, D10056, S70439, BC019811, AK010926, BC053338
Ensembl: ENSMUSG00000000049
KO: mmu:11818
Nucleutide sequences
EMBL-CDS: AAH19811.1, BAA00945.1, CAA72190.1, AAB30789.1, AAH53338.1, BAB27271.1
Ensembl_TRS: ENSMUST00000000049
Protein sequencees
Ensembl_PRO: ENSMUSP00000000049
RefSeq: NP_038503.4, XP_006532105.1
Others
UniRef100: UniRef100_Q9CY42, UniRef100_Q01339
UniRef90: UniRef90_Q01339
UniRef50: UniRef50_Q01339
UniGene: Mm.2266
CCDS: CCDS25574.1

全选

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