Tra2b - transformer 2 beta homolog-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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117259 Tra2b

基因描述

Type	Description
Definition	transformer 2 beta homolog

研究结论

Date	Results	Publications
2015-01-24 11:29:00	Tra2beta regulates the expression of RGS4 gene and is induced by morphine.	23977258
2013-10-19 11:10:00	increased expression and leakage of Omi/HtrA2 enhanced MI/R injury in aging hearts via degrading XIAP and promoting myocardial apoptosis.	22535253
2010-01-21 00:00:00	it is proposed that Tra2beta has been conserved through evolution and redeployed for the specification of the fast smooth muscle phenotype and may serve as a novel nodal point for the investigation of this process in developmental and disease models	18669920
2010-01-21 00:00:00	Results suggest that Tra2beta may regulate cellular oxidative response by changing alternative splicing of distinct genes including CD44.	19439532

名称对应

Type	IDs
Synonymous	Sfrs10, Srsf10
Gene	UniProtKB-ID: TRA2B_RAT UniprotKB: P62997 UniParc: UPI00000040A0 EMBL: D49708, BC070948 Ensembl: ENSRNOG00000001783 KO: rno:117259
Nucleutide sequences	EMBL-CDS: AAH70948.1, BAA08556.1 Ensembl_TRS: ENSRNOT00000002429
Protein sequencees	Ensembl_PRO: ENSRNOP00000002429 RefSeq: NP_476460.1, XP_008767012.1, XP_006248598.1
Others	UniRef100: UniRef100_P62995 UniRef90: UniRef90_P62995 UniRef50: UniRef50_P62995 UniGene: Rn.8538

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
25689357	Regulation of RAGE splicing by hnRNP A1 and Tra2Î²-1 and its potential role in AD pathogenesis. J. Neurochem. Xiao-Yan Liu , Hong-Lei Li , Jia-Bin Su , Fei-Hong Ding , Jing-Jing Zhao , Fang Chai , Yuan-Xin Li , Shi-Cao Cui , Feng-Yan Sun , Zhi-Ying Wu , Ping Xu , Xian-Hua Chen	2015-04-01	-
24586484	Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS ONE Markus Storbeck , Kristina Hupperich , John Antonydas Gaspar , Kesavan Meganathan , Lilian MartÃnez Carrera , Radu Wirth , Agapios Sachinidis , Brunhilde Wirth	2014-01-01	Tra2a, Casp3, Eomes, Kif11, Mki67, Mapt, Slu7, Tra2b, Sox6, Nrg1, Tcf4, Top2a, Nasp, Tubd1, Sgol2a, Cltb
23932931	The expression analysis of Sfrs10 and Celf4 during mouse retinal development. Gene Expr. Patterns Devi Krishna Priya Karunakaran , Sean Congdon , Thomas Guerrette , Abdul Rouf Banday , Christopher Lemoine , Nisarg Chhaya , Rahul Kanadia	2013-12-01	Celf4, Opn1mw, Glul, Isl1, Lamb2, Lmnb2, Prkca, Srsf2, Tra2b, Stx1a, Rho
22535253	Variations in the protein level of Omi/HtrA2 in the heart of aged rats may contribute to the increased susceptibility of cardiomyocytes to ischemia/reperfusion injury and cell death : Omi/HtrA2 and aged heart injury. Age (Dordr) Ke Wang , Jie Zhang , Jingyi Liu , Jue Tian , Ye Wu , Xiaoliang Wang , Lin Quan , Haibo Xu , Wen Wang , Huirong Liu	2013-06-01	Htra2, Tra2b, Diablo, Htra2, Xiap
24098751	Expression analysis of an evolutionarily conserved alternative splicing factor, Sfrs10, in age-related macular degeneration. PLoS One Devi Krishna Priya Karunakaran , Abdul Rouf Banday , Qian Wu , Rahul Kanadia	2013-01-01	-
23977258	Splicing factor transformer-2Î² (Tra2Î²) regulates the expression of regulator of G protein signaling 4 (RGS4) gene and is induced by morphine. PLoS ONE Shu-Jing Li , Ya Li , Shi-chao Cui , Yao Qi , Jing-Jing Zhao , Xiao-Yan Liu , Ping Xu , Xian-Hua Chen	2013-01-01	Tra2b, Rgs4
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell Alfredo Castello , Bernd Fischer , Katrin Eichelbaum , Rastislav Horos , Benedikt M Beckmann , Claudia Strein , Norman E Davey , David T Humphreys , Thomas Preiss , Lars M Steinmetz , Jeroen Krijgsveld , Matthias W Hentze	2012-06-08	GNPDA1, SCARNA27, GABPB1-AS1, NFYC-AS1, FKSG29, PHKA2-AS1, HDAC6, PDCD6, C17orf96, LOC100287042, MIR3652, ARPC4-TTLL3, ATP5J2-PTCD1, TGIF2-C20orf24, FARSB, ABCC5, ABCF2, HUWE1, ARPC4, ARPC1B, ACTR3, ACTR1A, LRPPRC, TRAP1, BCAP31, NAMPT, RBM12, TOB1, G3BP1, SUGP2, MBNL2, ABI2, CEBPZ, ATP6AP2, SLC25A15, RCL1, RBM7, RBM6, RBM5, ALYREF, PSME3, MPHOSPH10, NUTF2, USPL1, DDX39A, STX6, HNRNPR, MRPS31, RIDA, SF3B4, AKAP8, STUB1, SIGMAR1, SMNDC1, BCAS2, SF3A1, CDKN2A, APBB3, SMYD5, ADAR, EMC8, NPM3, HMG20A, NOD1, RACK1, NDC80, NSA2, YAP1, CD2BP2, TUBGCP3, RBM14, EMG1, ACAA2, PPIE, TAB1, MAD2L2, PIBF1, SLC25A17, NXF1, CREB3, LRRC41, SYNCRIP, ENOX2, MYBBP1A, DDX17, ADARB2, CHERP, HYOU1, IPO8, NOP56, RNASEH2A, GLRX3, DCTN2, LAMTOR5, PRDX4, AGPAT1, RPP30, SLU7, MRPL28
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell Alexander G Baltz , Mathias Munschauer , BjÃ¶rn SchwanhÃ¤usser , Alexandra Vasile , Yasuhiro Murakawa , Markus Schueler , Noah Youngs , Duncan Penfold-Brown , Kevin Drew , Miha Milek , Emanuel Wyler , Richard Bonneau , Matthias Selbach , Christoph Dieterich , Markus Landthaler	2012-06-08	NBPF10, TSFM, LRPPRC, RBM12, G3BP1, SUGP2, MBNL2, CEBPZ, TRIM28, RBM7, RBM6, RBM5, ALYREF, MPHOSPH10, EIF1, DDX39A, HNRNPR, MRPS31, POP7, SRRM1, SF3B4, AKAP8, LOC400927-CSNK1E, SAP18, EIF1B, SF3A1, CDKN2A, ADAR, NPM3, RACK1, NSA2, ADARB1, RBM14, EMG1, NXF1, SYNCRIP, MYBBP1A, DDX17, CHERP, NOP56, PRPF8, IGF2BP1, IGF2BP3, IGF2BP2, KHDRBS3, KHDRBS1, CELF1, CELF2, KIF1C, SRSF10, UTP14A, CPSF4, TCERG1, RNPS1, SUB1, SRSF8, SF3A3, HNRNPA0, EBNA1BP2, CKAP4, ASCC3, GCN1, SF3B2, NUDT21, CPSF6, DDX52, CHD2, DUSP14, DIDO1, NUPL2, HNRNPUL1, KRR1, LSM6, PSIP1, STRAP, SUPT16H, MRPL3, ATXN2L, LARP4, DDX42, PDAP1, U2AF2, WBSCR22, KCTD12, CIRBP, MRPL54, FTSJ3, EXOSC6, CHCHD1, CLK3, CLTC, HIST4H4, ZC3H18, MSI2, MRPL10, RAVER1, C1orf131, RBM45, CPEB2
22194695	Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2Î² in development. PLoS Genet. Sushma Grellscheid , Caroline Dalgliesh , Markus Storbeck , Andrew Best , Yilei Liu , Miriam Jakubik , Ylva Mende , Ingrid Ehrmann , Tomaz Curk , Kristina Rossbach , Cyril F Bourgeois , James StÃ©venin , David Grellscheid , Michael S Jackson , Brunhilde Wirth , David J Elliott	2011-12-01	Tra2a, Tra2b, Nasp
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-

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