| Type | Description |
|---|---|
| Definition | ubiquitin-conjugating enzyme E2N |
| Date | Results | Publications |
|---|---|---|
| 2018-10-06 10:15:00 | Knockdown or conditional knockout of RNF8 or UBC13 in rodent cerebellar granule neurons robustly increases the number of parallel fiber presynaptic boutons and functional parallel fiber/Purkinje cell synapses. In contrast to the role of nuclear RNF8 in proliferating cells, RNF8 operates in the cytoplasm in neurons to suppress synapse differentiation. | 29097665 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
UBE2N_RAT
UniprotKB:
Q9EQX9
UniParc:
UPI00000E5A94
EMBL:
AB032739,
BC090072
Ensembl:
ENSRNOG00000058053
KO:
rno:116725
|
| Nucleutide sequences |
EMBL-CDS:
AAH90072.1,
BAB20414.1
Ensembl_TRS:
ENSRNOT00000089874
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000071283
RefSeq:
NP_446380.1
|
| Others |
UniRef100:
UniRef100_Q9EQX9
UniRef90:
UniRef90_Q9EQX9
UniRef50:
UniRef50_Q9EQX9
UniGene:
Rn.230134
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31006531 |
Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity. Cell Cristhian Cadena , Sadeem Ahmad , Audrey Xavier , Joschka Willemsen , Sehoon Park , Ji Woo Park , Seong-Wook Oh , Takashi Fujita , Fajian Hou , Marco Binder , Sun Hur |
2019-05-16 | - |
| 29097665 |
RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain. Nat Commun Pamela Valnegri , Ju Huang , Tomoko Yamada , Yue Yang , Luis A Mejia , Ha Y Cho , Anna Oldenborg , Azad Bonni |
2017-11-02 | - |
| 28039360 |
Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development. J Biol Chem Claudia Lentucci , Anna C Belkina , Carly T Cederquist , Michelle Chan , Holly E Johnson , Sherry Prasad , Amanda Lopacinski , Barbara S Nikolajczyk , Stefano Monti , Jennifer Snyder-Cappione , Bogdan Tanasa , M Dafne Cardamone , Valentina Perissi |
2017-02-17 | - |
| 25936802 |
The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation. Mol. Cell Lu Deng , Cong Jiang , Lei Chen , Jiali Jin , Jie Wei , Linlin Zhao , Minghui Chen , Weijuan Pan , Yan Xu , Hongshang Chu , Xinbo Wang , Xin Ge , Dali Li , Lujian Liao , Mingyao Liu , Li Li , Ping Wang |
2015-06-04 |
Rnf152,
NPRL2,
RRAGA,
RNF152,
MTOR,
RRAGC,
TSC2,
UBE2N,
NPRL3,
DEPDC5
|
| 24326623 |
Double-strand break repair: 53BP1 comes into focus. Nat. Rev. Mol. Cell Biol. Stephanie Panier , Simon J Boulton |
2014-01-01 | - |
| 23533145 |
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics Simona Principe , E Ellen Jones , Yunee Kim , Ankit Sinha , Julius O Nyalwidhe , Jasmin Brooks , O John Semmes , Dean A Troyer , Raymond S Lance , Thomas Kislinger , Richard R Drake |
2013-05-01 | - |
| 23376485 |
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , Agnès Pernin , Jürg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll |
2013-04-26 |
CDH2,
GNPDA1,
C1orf68,
PDCD6IP,
PDCD6,
TOM1L1,
CDH6,
IL18BP,
DPP3,
SNUPN,
ARPC5,
CDH11,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
TSPAN1,
ARPC2,
ACTR1B,
ACTR1A,
CDH13,
PDIA6,
TRAP1,
PDZK1IP1,
ATP6AP2,
DHRS2,
NUTF2,
FLOT1,
PSMD14,
RIDA,
GLYAT,
ZMPSTE24,
STUB1,
RTN3,
LANCL1,
CRISP3,
SIRPB1,
AKR1A1,
TFG,
TUBA1B,
BPNT1,
TUBB4B,
BTN2A2,
NDRG1,
RACK1,
ST3GAL6,
CPQ,
WFDC2,
BASP1,
IFITM3,
CDSN,
LYPLA1,
FAM3C,
ACAA2,
VAV3,
TOMM40,
BAIAP2,
ATP5H,
CEACAM5,
CAP1,
VAT1,
FBLN5,
CIB1,
GLRX3,
PROCR,
ARL6IP5,
ARPC1A,
OLFM4,
CEL,
CCT7,
CCT4,
CCT2,
NPC2,
DNPH1,
PAICS,
MYL12A,
ATP5L,
YKT6,
PMVK,
GNA13,
B3GNT2,
CCT8,
CETP,
CFL1,
PTGES3,
RBBP9,
MASP2,
CTSC,
GIPC1,
AHCYL1,
IQGAP2,
VAMP5,
CFTR,
ALDH1L1,
FTCD,
RUVBL2,
PGRMC1,
FGL2
|
| 22797923 |
J. Cell. Sci. Gerta Hoxhaj , Ayaz Najafov , Rachel Toth , David G Campbell , Alan R Prescott , Carol MacKintosh |
2012-10-01 | - |
| 22871113 |
Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J. Proteome Res. Chan Hyun Na , Drew R Jones , Yanling Yang , Xusheng Wang , Yanji Xu , Junmin Peng |
2012-09-07 |
Rab1b,
Tmem59,
Msh6,
LOC100360426,
Sncb,
Csnk1a1,
Magi2,
Cxcl2,
Dnm1l,
Gng3,
Hcn2,
Clasp2,
Ubqln1,
Gne,
Stx1a,
Txn1,
Sec14l2,
Gripap1,
Mprip,
Slc6a9,
Ralb,
Ap2m1,
Nrxn2,
Slc17a7,
Vcp,
Cap2,
Dlgap2,
Lmnb1,
Trim28,
Epb41l3,
Ube2n,
Gp1bb,
Nup155,
Bin1,
Rpl6,
H3f3b,
Nlgn2,
Prdx1,
Psmc4,
Psmc1,
Epn1,
Ppp2r1a,
Hnrnpk,
Lrrc7,
Txnip,
Uba3,
Sv2b,
Tpm3,
Sv2a,
Atp6v1b2,
Rps20,
Slc8a2,
Rps3,
Faf1,
Ap2b1,
Dnm1,
Cacng8,
Cdk5,
Txnl1,
Ggt7,
Prkcd,
Palm,
Atp2c1,
Dynlrb1,
Kcnh7,
Xpnpep1,
Atxn10,
Kcnq2,
Cry2,
Rab3c,
Ndrg2,
Camk2g,
Pabpc1,
Eef1a1,
Slc12a5,
Acsbg1,
Tmem176b,
Nme1,
Tecr,
Syngap1,
Hip1,
Gpm6b,
Ehd4,
Rasgrf1,
Plpp3,
Stip1,
Caly,
Aldoa,
Aldoc,
Atp1a1,
Atp1a2,
Atp1a3,
Atp2b2,
Cacna1c,
Calm1,
Camk2d,
Ckb,
Eno1,
Gapdh
|
| 22681889 |
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell Alexander G Baltz , Mathias Munschauer , Björn Schwanhäusser , Alexandra Vasile , Yasuhiro Murakawa , Markus Schueler , Noah Youngs , Duncan Penfold-Brown , Kevin Drew , Miha Milek , Emanuel Wyler , Richard Bonneau , Matthias Selbach , Christoph Dieterich , Markus Landthaler |
2012-06-08 |
NBPF10,
TSFM,
LRPPRC,
RBM12,
G3BP1,
SUGP2,
MBNL2,
CEBPZ,
TRIM28,
RBM7,
RBM6,
RBM5,
ALYREF,
MPHOSPH10,
EIF1,
DDX39A,
HNRNPR,
MRPS31,
POP7,
SRRM1,
SF3B4,
AKAP8,
LOC400927-CSNK1E,
SAP18,
EIF1B,
SF3A1,
CDKN2A,
ADAR,
NPM3,
RACK1,
NSA2,
ADARB1,
RBM14,
EMG1,
NXF1,
SYNCRIP,
MYBBP1A,
DDX17,
CHERP,
NOP56,
PRPF8,
IGF2BP1,
IGF2BP3,
IGF2BP2,
KHDRBS3,
KHDRBS1,
CELF1,
CELF2,
KIF1C,
SRSF10,
UTP14A,
CPSF4,
TCERG1,
RNPS1,
SUB1,
SRSF8,
SF3A3,
HNRNPA0,
EBNA1BP2,
CKAP4,
ASCC3,
GCN1,
SF3B2,
NUDT21,
CPSF6,
DDX52,
CHD2,
DUSP14,
DIDO1,
NUPL2,
HNRNPUL1,
KRR1,
LSM6,
PSIP1,
STRAP,
SUPT16H,
MRPL3,
ATXN2L,
LARP4,
DDX42,
PDAP1,
U2AF2,
WBSCR22,
KCTD12,
CIRBP,
MRPL54,
FTSJ3,
EXOSC6,
CHCHD1,
CLK3,
CLTC,
HIST4H4,
ZC3H18,
MSI2,
MRPL10,
RAVER1,
C1orf131,
RBM45,
CPEB2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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