MRGPRD - MAS related GPR family member D-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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116512 MRGPRD

基因描述

Type	Description
Definition	MAS related GPR family member D

研究结论

Date	Results	Publications
2015-02-14 12:18:00	MRGD could be involved in tumorigenesis and could also be a novel anticancer drug target.	22715397
2013-06-22 11:02:00	Heptapeptide alamandine acts through Mas-related G-protein-coupled receptor member D producing physiological actions that resemble those generated by angiotensin-1-7.	23446738
2010-01-21 00:00:00	Mas, MrgD, and MRG mediated Ang IV-stimulated AA release that was highest for Mas. While Ang III activated Mas and MrgX2, Ang II stimulated AA release via Mas and MRG.	18636314

名称对应

Type	IDs
Synonymous	MRGD, TGR7
Gene	UniProtKB-ID: MRGRD_HUMAN UniprotKB: Q8TDS7 UniParc: UPI000003BCCA EMBL: AY427820, AB083627, AB154410, AB065786 Ensembl: ENSG00000172938 KO: hsa:116512
Nucleutide sequences	EMBL-CDS: AAR05120.1, BAB89340.1, BAD20638.1, BAC06005.1 Ensembl_TRS: ENST00000309106
Protein sequencees	Ensembl_PRO: ENSP00000310631 RefSeq: NP_944605.2
Others	UniRef100: UniRef100_Q8TDS7 UniRef90: UniRef90_Q8TDS7 UniRef50: UniRef50_Q8TDS7 UniGene: Hs.527802 CCDS: CCDS31625.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
23446738	Discovery and characterization of alamandine: a novel component of the renin-angiotensin system. Circ. Res. Roberto Queiroga Lautner , Daniel C Villela , Rodrigo A Fraga-Silva , Neiva Silva , Thiago Verano-Braga , Fabiana Costa-Fraga , Joachim Jankowski , Vera Jankowski , Frederico Sousa , Andreia Alzamora , Everton Soares , Claudiane Barbosa , Frank Kjeldsen , Aline Oliveira , Janaina Braga , Silvia Savergnini , Gisele Maia , Antonio Bastos Peluso , Danielle Passos-Silva , Anderson Ferreira , Fabiana Alves , Almir Martins , Mohan Raizada , Renata Paula , Daisy Motta-Santos , Friederike Klempin , Friederike Kemplin , Adriano Pimenta , Natalia Alenina , Ruben Sinisterra , Michael Bader , Maria Jose Campagnole-Santos , Robson A S Santos	2013-04-12	MRGPRD, AGT
22664934	Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. Oncol. Rep. Daniel BÃ¶hm , Ksenia Keller , Julia Pieter , Nils Boehm , Dominik Wolters , Wulf Siggelkow , Antje Lebrecht , Marcus Schmidt , Heinz KÃ¶lbl , Norbert Pfeiffer , Franz-Hermann Grus	2012-08-01	LOC101060157, USPL1, SCGB1D1, STAG3, MTHFD2, POP1, PRR4, ELFN2, MRGPRD, CLIC1, LRRK2, LRIG3, ZG16B, COL7A1, RBBP8NL, TTBK2, CST1, CST2, TMC8, CST4, DDB1, FREM3, DLG3, DMBT1, KRT78, ZFC3H1, SERPINB1, ENO1, ENO2, ENO3, ABCA3, ALB, ALDH3A1, CEP164, CNOT1, SIPA1L3, PMPCA, SULF1, KIAA0556, MCF2L, DMXL2, ZCCHC11, ALOX5, KLHL34, GNL3, KAT2A, MDGA1, GLE1, PRTG, LCN1P1, MRPL18, GSTP1, ANXA1, ANXA2, ANXA13, HP, HSPB1, APOA1, KLHL17, ACTBL2, IGHA1, IGHA2, IGHG2, IGHG3, IGHG4, JCHAIN, IGKC, IGLC1, IGLC2, MROH7, KRT1, KRT9, TRIM75P, LCN1, LCN2, LCP1, LGALS3, LOC400576, LTF, LYZ, MDH1, MECP2, SCGB2A1, MOV10, LOC439951, POTEE, ATP4A, PRDX1, PRKAG2, PDE4C, PIGR, PIP, PRKAG3, SEMA4C, LIME1, WDR60, NDUFAF7, ZNF446, SLF2
22715397	MRGD, a MAS-related G-protein coupled receptor, promotes tumorigenisis and is highly expressed in lung cancer. PLoS ONE Satoko Nishimura , Makiko Uno , Yasuyuki Kaneta , Keisuke Fukuchi , Haruyuki Nishigohri , Jun Hasegawa , Hironobu Komori , Shigeki Takeda , Katsuhiko Enomoto , Futoshi Nara , Toshinori Agatsuma	2012-01-01	MRGPRD
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18636314	Angiotensin metabolites can stimulate receptors of the Mas-related genes family. Mol Cell Biochem Florian Gembardt , Sonja Grajewski , Martin Vahl , Heinz-Peter Schultheiss , Thomas Walther	2008-12-01	-
15037633	Identification of a G protein-coupled receptor specifically responsive to beta-alanine. J Biol Chem Tokuyuki Shinohara , Masataka Harada , Kazuhiro Ogi , Minoru Maruyama , Ryo Fujii , Hideyuki Tanaka , Shoji Fukusumi , Hidetoshi Komatsu , Masaki Hosoya , Yuko Noguchi , Takuya Watanabe , Takeo Moriya , Yasuaki Itoh , Shuji Hinuma	2004-05-28	-
12909716	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Proc. Natl. Acad. Sci. U.S.A. Mark J Zylka , Xinzhong Dong , Amber L Southwell , David J Anderson	2003-08-19	-
12044878	Identification of G protein-coupled receptor genes from the human genome sequence. FEBS Lett. Shigeki Takeda , Shiro Kadowaki , Tatsuya Haga , Hirotomo Takaesu , Shigeki Mitaku	2002-06-05	-
11551509	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell X Dong , S Han , M J Zylka , M I Simon , D J Anderson	2001-09-07	-

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