| Type | Description |
|---|---|
| Definition | basic leucine zipper ATF-like transcription factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 11:32:00 | BATF2 was overexpressed in tissues from patients with non-responsive gastric cancer (GC) and the vincristine resistance cell line, SGC7901/VCR, while levels of c-Fos and c-Jun were reduced. AP-1 down-regulation by BATF2 overexpression or AP-1 knockdown can inhibit drug resistance in GC cells. These findings suggest that BATF2 inhibits DR in vincristine resistance GC cell line by down-regulating AP-1 expression. | 31549215 |
| 2019-12-21 12:25:00 | BATF2 role in the multidrug resistance of human gastric cancer cells and the regulation of the Wnt/beta-catenin signaling. | 31140101 |
| 2019-06-15 10:51:00 | BATF2 gene expression is associated with tuberculosis in the HIV infected patients. | 29764370 |
| 2017-12-16 12:18:00 | BATF2 gene was modulated after treatment with zebularine and was a poor prognostic marker, since its low levels were correlated with relapse and a poor prognosis for medulloblastoma patients. | 27785591 |
| 2017-11-26 01:02:00 | Gain- and loss-of-function studies uncovered a role for Batf2 in myeloid differentiation in both murine and human systems. We thus demonstrate that chronic infection can deplete HSPCs and identify BATF2 as a mediator of infection-induced HSPC terminal differentiation | 27926863 |
| Type | IDs |
|---|---|
| Synonymous | SARI |
| Gene |
UniProtKB-ID:
BATF2_HUMAN,
B4DV37_HUMAN
UniprotKB:
Q8N1L9,
B4DV37
UniParc:
UPI000006F277,
UPI00017A7DC5,
UPI000006E749
EMBL:
AK300917,
HM134154,
BC012330,
AK096702,
AK092453,
AP000436,
CH471076,
AK092761
Ensembl:
ENSG00000168062
KO:
hsa:116071
|
| Nucleutide sequences |
EMBL-CDS:
BAC03894.2,
BAC04846.1,
BAC03968.2,
AAH12330.1,
EAW74330.1,
ADJ55304.1,
BAG62549.1
Ensembl_TRS:
ENST00000301887,
ENST00000435842,
ENST00000527716
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398911,
ENSP00000301887,
ENSP00000434915
RefSeq:
NP_001287736.1,
NP_612465.3,
NP_001287737.1
|
| Others |
UniRef100:
UniRef100_B4DV37,
UniRef100_Q8N1L9
UniRef90:
UniRef90_B4DV37,
UniRef90_Q8N1L9
UniRef50:
UniRef50_B4DV37,
UniRef50_Q8N1L9
UniGene:
Hs.124840
CCDS:
CCDS73317.1,
CCDS8087.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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