| Type | Description |
|---|---|
| Definition | adenylosuccinate synthetase like 1 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | The absence of the 2'-hydroxyl group of the deoxyribonucleotide destabilizes binding of the ligand to the L-aspartate pocket of adenylosuccinate synthetase by disrupting hydrogen bonds and by introducing a cavity into the fully ligated active site. | 16981730 |
| 2010-01-21 00:00:00 | there are antagonistic interactions between the active sites of the basic isozyme of adenylosuccinate synthetase | 12482871 |
| 2010-01-21 00:00:00 | Deletion of Adenylosuccinate synthetase 1 gene is associated with lung adenocarcinoma. | 19603421 |
| 2010-01-21 00:00:00 | Crystalline complexes presented of the recombinant basic isozyme from mouse | 12004071 |
| 2010-01-21 00:00:00 | Adss1 functions as an important component in adenine nucleotide biosynthesis. It is up-regulated in surgically induced cardiomegaly. | 12169208 |
| Type | IDs |
|---|---|
| Synonymous | AI528595, Adss, Adss1 |
| Gene |
UniProtKB-ID:
PURA1_MOUSE,
Q3UBP0_MOUSE
UniprotKB:
P28650,
Q3UBP0
UniParc:
UPI00000E8D3C,
UPI0000021B84
EMBL:
AK150874,
AK146907,
BC039943,
M74495
Ensembl:
ENSMUSG00000011148
KO:
mmu:11565
|
| Nucleutide sequences |
EMBL-CDS:
AAA82870.1,
AAH39943.1,
BAE27520.1,
BAE29924.1
Ensembl_TRS:
ENSMUST00000021726
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021726
RefSeq:
NP_031447.1
|
| Others |
UniRef100:
UniRef100_P28650
UniRef90:
UniRef90_P28650
UniRef50:
UniRef50_P28650
UniGene:
Mm.3440
CCDS:
CCDS26192.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 23341629 |
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc. Natl. Acad. Sci. U.S.A. Stephen Lumayag , Caroline E Haldin , Nicola J Corbett , Karl J Wahlin , Colleen Cowan , Sanja Turturro , Peter E Larsen , Beatrix Kovacs , P Dane Witmer , David Valle , Donald J Zack , Daniel A Nicholson , Shunbin Xu |
2013-02-05 |
Mthfsl,
Ildr2,
Copg2os2,
Rell1,
Lrrc8c,
Mirc35hg,
Meig1,
Mbnl2,
Mthfs,
Galnt7,
Lmo1,
Cald1,
Cbr3,
Tmbim6,
Msra,
H2,
Abca1,
Ache,
Chrnb1,
Rasa2,
Adssl1,
Prelp,
Iltifb,
Aox1,
Aqp1,
B2m,
Bcl6,
Serping1,
C1qc,
C4b,
Cacna2d3,
Casp7,
Cd44,
Cd9,
Cfi,
Col4a3,
Cp,
Cr1l,
Crym,
Ctbp2,
Cttn,
Dlg4,
Doc2b,
Edn2,
Emx1,
Enc1,
Ephb3,
Ephx2,
Eri3,
Folr1,
Opn1mw,
Gfap,
Glycam1,
Gna14,
Gnb2,
Pdpn,
Gpm6b,
Ptpn6,
Hdc,
Hsd17b2,
Sdc2,
Mdfic,
Kifc3,
Laptm5,
Gzmm,
Arr3,
Lyz2,
Mab21l1,
Marcks,
Mcl1,
Mcm3,
Mef2c,
Mesp1,
Myo10,
Slc25a15,
Osmr,
Lgals3bp,
Psen2,
Tmsb4x,
Pygm,
Rab3d,
Rps17,
S100a1,
S100a6,
Ccl9,
Exoc4,
Sema3b,
Sez6,
Sh2d1a,
Slc12a4,
Slc16a2,
Slc19a1,
Slc1a1,
Slc6a2,
Dtx4,
Klhl29,
Snx30,
Sdc3,
Mtss1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 20798045 |
Proc Natl Acad Sci U S A João D Pereira , Stephen N Sansom , James Smith , Marc-Werner Dobenecker , Alexander Tarakhovsky , Frederick J Livesey |
2010-09-07 | - |
| 19603421 |
Adenylosuccinate synthetase 1 gene is a novel target of deletion in lung adenocarcinoma. Mol. Carcinog. Joshua C Miller , Daniel C Blake , Christopher R Herzog |
2009-12-01 |
Adssl1
|
| 17904117 |
Dev. Biol. Judith K Davie , Jang-Hyeon Cho , Eric Meadows , Jesse M Flynn , Jennifer R Knapp , William H Klein |
2007-11-15 |
Cdc42ep2,
Actn2,
Adssl1,
Fgfrl1,
Casq2,
Cox6a2,
Cox8b,
Csrp3,
Dclk1,
Enah,
Fgf6,
Myf5,
Myf6,
Myh1,
Myod1,
Myog,
Myom2,
Nov,
Tcea3,
Tnni2,
Ttn,
Zyx,
Ampd1,
Ldb3,
Itgb1bp2,
Srpk3,
Myoz2,
Myoz1,
Smpx,
Arhgap36,
Ckmt2,
Lmod2
|
| 16981730 |
Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases. Biochemistry Cristina V Iancu , Yang Zhou , Tudor Borza , Herbert J Fromm , Richard B Honzatko |
2006-09-26 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 15782199 |
Nat. Methods Akira Watahiki , Kazunori Waki , Norihito Hayatsu , Toshiyuki Shiraki , Shinji Kondo , Mari Nakamura , Daisuke Sasaki , Takahiro Arakawa , Jun Kawai , Matthias Harbers , Yoshihide Hayashizaki , Piero Carninci |
2004-12-01 |
Ldlrap1,
Mfap1b,
Dnajc3,
Fam129c,
Rsph3b,
Rnaset2a,
Fam174b,
Gm9797,
Gm2296,
Gm15429,
Atp6v0c-ps2,
Kcnj13,
Gm10291,
Gm15264,
Rpl3-ps1,
Gm4482,
Srcap,
Tpt1-ps3,
Rps2-ps6,
Orai2-ps,
Tdrd7,
Sco2,
Pafah2,
Akna,
H6pd,
Stx12,
Gm15590,
Osbpl9,
AU040320,
Ppp1r8,
Bsdc1,
Gm37013,
Slc44a1,
Zfand2a,
Rpl5,
LOC100503956,
Atg14,
Rell1,
Slc15a4,
Noc4l,
Psph,
9330133O14Rik,
Mapre3,
Usp30,
Ube3c,
Rita1,
Tbc1d14,
Gm21685,
Chpf2,
Tyw1,
Rab28,
Zfp513,
LOC101055802,
Zfp282,
Snx21,
Rpusd3,
Itfg2,
Pot1a,
Tada3,
Brk1,
Eogt,
Dhx32,
Ric8a,
Inpp5f,
Plekhg2,
Hsd3b7,
Mob2,
Prkd2,
Vrk3,
Grwd1,
Pwwp2b,
Spty2d1,
Faap24,
Ints4,
Rrp8,
Unc45a,
Sf3b3,
D8Ertd738e,
Usb1,
Smim19,
Dohh,
Fam192a,
Enkd1,
Prmt9,
Zdhhc7,
Snapc2,
Gpat4,
Ankrd10,
Cog4,
Clk3,
Xylb,
Imp3,
Cmtm7,
Ano10,
Alg9,
Plekho2,
Mapkapk3,
Acad11,
Gm30491
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员