| Type | Description |
|---|---|
| Definition | adrenergic receptor, alpha 2a |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:12:00 | alpha2A-adrenoceptor deficiency attenuates lipopolysaccharide-induced lung injury by increasing norepinephrine levels and inhibiting alveolar macrophage activation in acute respiratory distress syndrome. | 32643759 |
| 2020-08-29 12:44:00 | The in vivo specificity of synaptic Gbeta and Ggamma subunits to the alpha2a adrenergic receptor at CNS synapses. | 30737458 |
| 2019-10-12 11:53:00 | Study shows that dorsal BNST alpha2A-adrenergic receptors produce HCN-dependent excitatory actions that initiate anxiogenic behaviors. | 30150361 |
| 2019-09-28 13:24:00 | Lack of alpha2A-ARs protects from diet-induced obesity and type 2 diabetes (T2D). Blockade of alpha2A-ARs may be exploited to reduce visceral fat and to improve insulin secretion. | 30041171 |
| 2019-07-06 10:50:00 | We show that these neurons are dispensable for regulating food intake, but are required for coordinating hepatic glucose production and for the fasting-induced fall in leptin levels, independent of changes in fat mass. We also identify a role for sympathetic nervous system regulation of the inhibitory adrenergic receptor (ADRA2A) in regulating leptin production. | 29528284 |
| Type | IDs |
|---|---|
| Synonymous | AW122659, Adra-2, Adra-2a, alpha(2A)AR, alpha2-C10, alpha2A, alpha2A-AR |
| Gene |
UniProtKB-ID:
ADA2A_MOUSE
UniprotKB:
Q01338
UniParc:
UPI00003559D2
EMBL:
M99377,
AK141573,
BC138531,
AC113491
Ensembl:
ENSMUSG00000033717
KO:
mmu:11551
|
| Nucleutide sequences |
EMBL-CDS:
AAI38532.1,
BAE24742.1,
AAA37213.1
Ensembl_TRS:
ENSMUST00000036700,
ENSMUST00000237285
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036203,
ENSMUSP00000157421
RefSeq:
NP_031443.4
|
| Others |
UniRef100:
UniRef100_Q01338
UniRef90:
UniRef90_P22909
UniRef50:
UniRef50_P08913
UniGene:
Mm.235195,
Mm.489007
CCDS:
CCDS29905.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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