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11321 GPN1

11321

GPN1

GPN-loop GTPase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition GPN-loop GTPase 1

研究结论

Date Results Publications
2017-12-16 10:31:00 Results show that Gpn1-inhibitable, nuclear polyubiquitination on lysine 216 regulates the half-life of Gpn3 by tagging it for proteasomal degradation. 29029378
2017-11-25 15:40:00 an acquired PDZ-binding motif in Gpn3 Q279* caused Gpn3 nuclear entry, and inhibited Gpn1 nuclear export and Gpn3-mediated RNAPII nuclear targeting. 28940195
2017-09-09 10:38:00 GPN1 gene variation is associated with oral cavity and pharyngeal cancer. 27749845
2015-01-24 11:31:00 Gpn1-Gpn3 interaction was essential to maintain steady-state protein levels of both GTPases 25241168
2012-11-24 10:13:00 A highly active, evolutionarily conserved nuclear export sequences in XAB1/Gpn1, was identified. 22796641

名称对应

Type IDs
Synonymous ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1
Gene
UniProtKB-ID: GPN1_HUMAN, Q53RZ9_HUMAN
UniprotKB: Q9HCN4, Q53RZ9
UniParc: UPI00017A77BC, UPI00017A82C7, UPI000173A56D, UPI000006E7AC, UPI00017A7757
EMBL: AK298827, AK302131, AK312992, AK298866, CH471053, AK316404, AJ010842, AC074091, AK310340, BC007451, AB044661
Ensembl: ENSG00000198522
KO: hsa:11321
Nucleutide sequences
EMBL-CDS: BAG60986.1, BAG60957.1, BAB17612.1, BAH14775.1, BAG63506.1, CAA09376.1, AAH07451.1, AAX93201.1, EAX00558.1, BAG35829.1
Gene_ORFName: HUSSY-23, hCG_21230
Ensembl_TRS: ENST00000458167, ENST00000503738, ENST00000616939, ENST00000424214, ENST00000610189, ENST00000264718, ENST00000407583, ENST00000515877
Protein sequencees
Ensembl_PRO: ENSP00000384255, ENSP00000427269, ENSP00000484680, ENSP00000424678, ENSP00000398115, ENSP00000412170, ENSP00000264718, ENSP00000476446
RefSeq: NP_009197.3, NP_001138520.1, NP_001138521.1, NP_001138519.1
Others
UniRef100: UniRef100_Q9HCN4
UniRef90: UniRef90_Q9HCN4
UniRef50: UniRef50_Q9HCN4
UniGene: Hs.18259
CCDS: CCDS46250.1, CCDS46248.1, CCDS1760.2, CCDS46249.1

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