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112406 Egln2

112406

Egln2

egl-9 family hypoxia-inducible factor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition egl-9 family hypoxia-inducible factor 2

研究结论

Date Results Publications
2020-10-10 13:01:00 Endothelial prolyl hydroxylase 2 is necessary for angiotensin II-mediated renal fibrosis and injury. 32715763
2020-04-04 11:43:00 PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase. The ability of PHD1 to promote mTORC1 activity is independent of its hydroxylation activity but is caused by decreased protein content of the leucyl tRNA synthetase (LRS) leucine sensor. 31924757
2019-07-13 12:25:00 Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-kappaB and p53 signaling pathways 29222481
2018-09-01 11:15:00 HS-induced PPARalpha-mediated downregulation of PHD1 is a novel pathway for PHD/HIF-1alpha transcriptional regulation. 29500923
2018-02-24 11:50:00 EglN2 might act as an FBW7 ubiquitin ligase substrate contributing to the progression of triple negative breast cancer. 28036276

名称对应

Type IDs
Synonymous 0610011A13Rik, C85656, Hif-p4h-1, Ier4, Phd1, SM-20
Gene
UniProtKB-ID: EGLN2_MOUSE, Q80X29_MOUSE
UniprotKB: Q91YE2, Q80X29
UniParc: UPI0000020D88
EMBL: AK152223, BC086764, AJ310547, AF453879, BC023299, BC051436, AF340231, AK075582
Ensembl: ENSMUSG00000058709
KO: mmu:112406
Nucleutide sequences
EMBL-CDS: AAH23299.2, AAL65166.1, CAC42516.1, AAK37525.1, BAC35835.1, BAE31050.1, AAH86764.1, AAH51436.1
Ensembl_TRS: ENSMUST00000080058, ENSMUST00000108382
Protein sequencees
Ensembl_PRO: ENSMUSP00000104019, ENSMUSP00000078966
RefSeq: NP_001344696.1, XP_030097849.1, NP_444438.2, XP_030097851.1, XP_030097850.1, XP_036008464.1
Others
UniRef100: UniRef100_Q91YE2
UniRef90: UniRef90_Q6AYU4
UniRef50: UniRef50_Q6AYU4
UniGene: Mm.29978
CCDS: CCDS21011.1

全选

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