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11181 TREH

11181

TREH

trehalase

protein-coding

Homo sapiens

基因描述

Type Description
Definition trehalase

研究结论

Date Results Publications
2018-06-09 10:56:00 these results indicate that trehalose has anti-apoptotic effects through the suppression of oxidative stress-induced mitochondrial injury and ER stress which is dependent on the promotion of autophagic flux and the induction of selective autophagy 28981117
2017-05-13 10:46:00 In conclusion, we identified four novel loci (TGFA, PIK3R1, FGFR3 and TREH) and confirmed two loci known to be associated with cartilage thickness.The identified associations were not caused by rare exonic variants. This is the first report linking TGFA to human Osteoarthritis, which may serve as a new target for future therapies. 27701424
2016-04-16 11:34:00 results suggest a significant association between the RETL1, TREH, and PHLDB1 genes and GBM development in the Han Chinese population 26156397
2013-07-13 13:09:00 variants in TREH control trehalase activity, and although one of these variants is also reproducibly associated with T2D, it is likely that the effect of the SNP on risk of T2D occurs by a mechanism different than affecting trehalase activity. 23468175
2012-09-22 10:14:00 we found three protective alleles for glioma patients, including the allele ''T'' of rs17748 in the TREH gene by recessive model (OR, 0.48; 95% CI, 0.23-1.01; P = 0.05) analysis 22369735

名称对应

Type IDs
Synonymous TRE, TREA, TREHD
Gene
UniProtKB-ID: TREA_HUMAN
UniprotKB: O43280
UniParc: UPI00005DC752, UPI000013D4A6
EMBL: AB000824, CH471065, AK223143, BC109206, AK223140
Ensembl: ENSG00000118094
KO: hsa:11181
Nucleutide sequences
EMBL-CDS: AAI09207.1, EAW67409.1, BAD96860.1, BAA24381.1, BAD96863.1
Ensembl_TRS: ENST00000397925, ENST00000264029
Protein sequencees
Ensembl_PRO: ENSP00000264029, ENSP00000381020
RefSeq: NP_001287994.1, NP_009111.2
Others
UniRef100: UniRef100_O43280
UniRef90: UniRef90_O43280
UniRef50: UniRef50_O43280
UniGene: Hs.129712
CCDS: CCDS73401.1, CCDS73402.1

全选

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