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109731 Maob

109731

Maob

monoamine oxidase B

protein-coding

Mus musculus

基因描述

Type Description
Definition monoamine oxidase B

研究结论

Date Results Publications
2020-05-02 12:05:00 We have developed a potent, highly selective, and reversible MAO-B inhibitor, KDS2010 (IC50 = 7.6 nM; 12,500-fold selectivity over MAO-A), which overcomes the disadvantages of the irreversible MAO-B inhibitor 30906861
2019-08-17 10:14:00 mice lacking both MAO isoforms, MAOA and MAOB, exhibit smaller prostate mass and develop epithelial atrophy in the ventral and dorsolateral prostates. 29637670
2019-02-23 13:08:00 findings thus support that AEP-mediated cleavage of alpha-Syn at N103 is required for the association and activation of MAO-B, mediating Parkinson's disease pathogenesis. 29769405
2017-06-03 12:08:00 Hydralazine (Hdz) abrogated the degradation of tele-methylhistamine (tMH) catalyzed by monoamine oxidase B (MAO-B) in vitro. 28069864
2016-09-03 10:25:00 Huntington disease neural cells exhibit increased Monoamine oxidase-A and Monoamine oxidases-B expression and activity 25398695

名称对应

Type IDs
Synonymous 6330414K01Rik, MAO-B
Gene
UniProtKB-ID: AOFB_MOUSE
UniprotKB: Q8BW75
UniParc: UPI000019386E
EMBL: BC113788, AL831729, AL732321, CH466584, BC113182, AK054050, AK031833
Ensembl: ENSMUSG00000040147
KO: mmu:109731
Nucleutide sequences
EMBL-CDS: BAC27571.1, EDL35718.1, AAI13789.1, BAC35634.1, AAI13183.1
Ensembl_TRS: ENSMUST00000040820
Protein sequencees
Ensembl_PRO: ENSMUSP00000040550
RefSeq: NP_766366.2
Others
UniRef100: UniRef100_Q8BW75
UniRef90: UniRef90_Q8BW75
UniRef50: UniRef50_P19643
UniGene: Mm.241656
CCDS: CCDS40882.1

全选

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研究热度

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