Type | Description |
---|---|
Definition | SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
Date | Results | Publications |
---|---|---|
2019-06-29 11:14:00 | REVIEW: cellular function of S100A6 and its ligands, CacyBP/SIP and Sgt1 | 30656909 |
2018-06-02 10:30:00 | the SGT1-HSP90 complex contributes to the E3 ligase activity of the CUL4A complex that is necessary for CENP-A ubiquitylation and CENP-A deposition at the centromere. | 28816574 |
2017-09-16 11:57:00 | Data suggest that PHLPP1 plays an important role in assembly of kinetochores by counteracting RNF41-mediated SGT1 degradation. (PHLPP1 = PH domain and leucine rich repeat protein phosphatase 1; RNF41 = ring finger protein 41; SGT1 = suppressor of G2 allele of SKP1) | 28696259 |
2017-06-24 12:19:00 | Fusion of human SGT1 (hSGT1) to NOD1 LRR significantly enhanced the solubility, and the fusion protein was stabilized by coexpression of mouse Hsp90alpha. | 27591899 |
2016-12-17 10:11:00 | Data (including data from studies using purified proteins/hepatocyte lysates) suggest eEF1A1/Sgt1a interact as multimer; D2/D3 domains of eEF1A1 and TPR domain of Sgt1 are involved in multimer formation; Sgt1 competes with viral RNA to bind to eEF1A. | 26545799 |
Type | IDs |
---|---|
Synonymous | SGT1 |
Gene |
UniProtKB-ID:
SGT1_HUMAN,
B4DYC6_HUMAN,
A8K7W3_HUMAN
UniprotKB:
Q9Y2Z0,
B4DYC6,
A8K7W3
UniParc:
UPI00015DA9F7,
UPI00001CDFF4,
UPI000006D6DA,
UPI00017A8203
EMBL:
CH471124,
AK292128,
AL139089,
BT009798,
AJ344097,
BC000911,
AK302363,
AY321358,
AY271314,
AF132856
Ensembl:
ENSG00000165416
KO:
hsa:10910
|
Nucleutide sequences |
EMBL-CDS:
AAQ76039.1,
AAP88800.1,
AAQ01749.1,
AAD30062.1,
AAH00911.1,
CAC51433.1,
EAW52045.1,
BAG63688.1,
BAF84817.1
Ensembl_TRS:
ENST00000310528,
ENST00000343788
|
Protein sequencees |
Ensembl_PRO:
ENSP00000367208,
ENSP00000308067
RefSeq:
XP_016875856.1,
XP_011533195.1,
XP_016875857.1,
XP_011533193.1,
NP_001307760.1,
NP_006695.1,
XP_016875855.1,
NP_001124384.1,
XP_016875854.1
|
Others |
UniRef100:
UniRef100_Q9Y2Z0,
UniRef100_B4DYC6,
UniRef100_A8K7W3
UniRef90:
UniRef90_Q2KIK0,
UniRef90_W5PA50,
UniRef90_Q9Y2Z0
UniRef50:
UniRef50_Q9Y2Z0
UniGene:
Hs.281902
CCDS:
CCDS45050.1,
CCDS9436.1
|
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