| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory subunit 15B |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 11:40:00 | CReP deletion activates a linear signaling pathway involving eIF2alpha phosphorylation, ATF4 translation, and FGF21 induction, which promotes increased energy expenditure, and subsequently improved obesity-related metabolic parameters. | 29698569 |
| 2017-05-20 10:57:00 | Results highlighted the essential roles played by GADD34 and CReP in regulating mRNA translation during unstressed conditions and following endoplasmic reticulum stress. | 27161320 |
| 2015-10-10 10:59:00 | CReP expression was markedly suppressed in XBP1-deficient mice livers due to hyperactivated Ire1alpha. | 26031337 |
| 2010-01-21 00:00:00 | Ppp1r15a mutant mice are superficially indistinguishable from wild type; Ppp1r15b(-/-) mouse embryos survive gestation but exhibit severe growth retardation and impaired erythropoiesis, and loss of both Ppp1r15 genes leads to early embryonic lethality | 19181853 |
| Type | IDs |
|---|---|
| Synonymous | 1810033K10Rik, AI606441, C530022L24Rik, CReP |
| Gene |
UniProtKB-ID:
PR15B_MOUSE
UniprotKB:
Q8BFW3
UniParc:
UPI00000274B8,
UPI00005B2724
EMBL:
AK167565,
AK086606,
AK144678,
AK170862,
AK146089,
AK049028,
AK082957
Ensembl:
ENSMUSG00000046062
KO:
mmu:108954
|
| Nucleutide sequences |
EMBL-CDS:
BAE26892.1,
BAC38708.1,
BAE26007.1,
BAE42079.1,
BAC33517.1,
BAE39628.1,
BAC39701.1
Ensembl_TRS:
ENSMUST00000052529
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000057062
RefSeq:
NP_598580.1
|
| Others |
UniRef100:
UniRef100_Q8BFW3
UniRef90:
UniRef90_Q8BFW3
UniRef50:
UniRef50_Q5SWA1
UniGene:
Mm.293628
CCDS:
CCDS15291.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32968282 |
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells. Nature Keith A Lawson , Cristovão M Sousa , Xiaoyu Zhang , Eiru Kim , Rummy Akthar , Joseph J Caumanns , Yuxi Yao , Nicholas Mikolajewicz , Catherine Ross , Kevin R Brown , Abdelrahman Abou Zid , Zi Peng Fan , Shirley Hui , Jordan A Krall , Donald M Simons , Chloe J Slater , Victor De Jesus , Lujia Tang , Richa Singh , Joshua E Goldford , Sarah Martin , Qian Huang , Elizabeth A Francis , Andrea Habsid , Ryan Climie , David Tieu , Jiarun Wei , Ren Li , Amy Hin Yan Tong , Michael Aregger , Katherine S Chan , Hong Han , Xiaowei Wang , Patricia Mero , John H Brumell , Antonio Finelli , Laurie Ailles , Gary Bader , Gromoslaw A Smolen , Gillian A Kingsbury , Traver Hart , Charles Kung , Jason Moffat |
2020-10-01 | - |
| 29698569 |
Hepatology Xu Xu , Christopher Krumm , Jae-Seon So , Curtis J Bare , Corey Holman , Jesper Gromada , David E Cohen , Ann-Hwee Lee |
2018-12-01 | - |
| 27161320 |
Mol Cell Biol David W Reid , Angeline S L Tay , Jeyapriya R Sundaram , Irene C J Lee , Qiang Chen , Simi E George , Christopher V Nicchitta , Shirish Shenolikar |
2016-07-01 | - |
| 26031337 |
Mol. Cell. Biol. Jae-Seon So , Sungyun Cho , Sang-Hyun Min , Scot R Kimball , Ann-Hwee Lee |
2015-08-01 |
Ppp1r15b,
Eif2s1,
Ern1
|
| 25737280 |
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes Dev. Jernej Murn , Kathi Zarnack , Yawei J Yang , Omer Durak , Elisabeth A Murphy , Sihem Cheloufi , Dilenny M Gonzalez , Marianna Teplova , Tomaž Curk , Johannes Zuber , Dinshaw J Patel , Jernej Ule , Nicholas M Luscombe , Li-Huei Tsai , Christopher A Walsh , Yang Shi |
2015-03-01 |
Sf3b3,
Pls3,
Xpo1,
Slc38a1,
Rrn3,
Hat1,
Ogt,
Foxp1,
Atp6v1h,
Pnrc1,
Ppp1r15b,
Pkn2,
Rap1a,
Acat1,
Cse1l,
Abcb7,
Actb,
Prdx3,
Ap1g1,
Arf1,
Arf4,
Arf5,
Arhgap5,
Atp2a2,
Atp5a1,
Atpif1,
Phb2,
Birc6,
Calm1,
Calm2,
Calm3,
Ctnna1,
Ctnnb1,
Cbx3,
Cbx5,
Cct4,
Cct5,
Cct8,
Cdc42,
Copa,
Cox5a,
Cox7a2,
Dpysl2,
Csnk2b,
Ctsb,
Dhx15,
Ddx5,
Dync1h1,
Dst,
Mapre1,
Eef1a1,
Eef2,
Eif3a,
Eif4a1,
Eif4a2,
Eif4g2,
Gdi1,
Gdi2,
Gfpt1,
Ggps1,
Gls,
Glud1,
Rack1,
Pdia3,
H3f3b,
Hdac2,
Hint1,
Hmgcr,
Hn1,
Hnrnpab,
Hnrnpl,
Hspd1,
Hsp90ab1,
Hsp90aa1,
Hspa4,
Hspa9,
Hspe1,
Id3,
Kpnb1,
Eif3e,
Itgb1,
Itm2b,
Kpna4,
Kpna6,
Kras,
Ldha,
Nup155,
Matr3,
Mcl1,
Msh6,
Laptm4a,
Nap1l4,
Ncl,
Nfib,
Ogdh,
Pdcd4,
Slc25a3,
Plaa,
Ppp1cb
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 19181853 |
Proc Natl Acad Sci U S A Heather P Harding , Yuhong Zhang , Donalyn Scheuner , Jane-Jane Chen , Randal J Kaufman , David Ron |
2009-02-10 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 18500982 |
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. BMC Dev. Biol. Paolo Cinelli , Elisa A Casanova , Syndi Uhlig , Priska Lochmatter , Takahiko Matsuda , Takashi Yokota , Thomas Rülicke , Birgit Ledermann , Kurt Bürki |
2008-01-01 |
Ppp1r15b,
Hk2,
Rhox5,
Stat3,
Skp2,
Lefty2,
Pramel6,
Pramel7,
Eif2s2,
Dppa3
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员