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1088 CEACAM8

1088

CEACAM8

carcinoembryonic antigen related cell adhesion molecule 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition carcinoembryonic antigen related cell adhesion molecule 8

研究结论

Date Results Publications
2021-02-02 13:26:00 CD66b(+) monocytes represent a proinflammatory myeloid subpopulation in cancer. 32632664
2020-04-11 10:52:00 High CEACAM8 expression is associated with metastases in breast carcinoma. 31222613
2017-09-23 12:40:00 Increased CD66b positive tumor-infiltrating neutrophils (CD66b + TINs) was significantly associated with presence of metastasis, S stage, and nonseminomatous germ cell tumor diagnosis. 27863478
2017-07-29 10:47:00 a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO, CEACAM8, CRISP3, MS4A3, CEACAM6, HEMGN, and MMP8 27579896
2016-04-30 11:30:00 Inhibition of C5aR1 leads to a significant reduction of CD66b and CD11b expression indicating a lower neutrophil activation status and block of granule exocytosis. 26176669

名称对应

Type IDs
Synonymous CD66b, CD67, CGM6, NCA-95
Gene
UniProtKB-ID: CEAM8_HUMAN, B4DLI3_HUMAN, Q0Z7S6_HUMAN
UniprotKB: P31997, B4DLI3, Q0Z7S6
UniParc: UPI00000012A3, UPI00017A7570
EMBL: CH471126, AC004558, AK297012, D90064, BC026263, X52378, M33326, Z95119, DQ822518, AK312652
Ensembl: ENSG00000124469
KO: hsa:1088
Nucleutide sequences
EMBL-CDS: AAA59914.1, AAH26263.1, CAA36604.1, CAB08298.1, AAC13659.1, BAA14108.1, BAG59545.1, BAG35535.1, EAW57144.1, ABG46943.1
Gene_ORFName: hCG_21882
Ensembl_TRS: ENST00000244336
Protein sequencees
Ensembl_PRO: ENSP00000244336
RefSeq: XP_011524643.1, XP_011524642.1, XP_016881687.1, XP_016881686.1, XP_016881685.1, XP_016881684.1, NP_001807.2, XP_011524644.1, XP_016881683.1
Others
UniRef100: UniRef100_B4DLI3, UniRef100_P31997
UniRef90: UniRef90_B4DLI3, UniRef90_P31997
UniRef50: UniRef50_A0A452TH46, UniRef50_P31997
UniGene: Hs.41
CCDS: CCDS12610.1

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