| Type | Description |
|---|---|
| Definition | mannoside acetylglucosaminyltransferase 5 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 10:20:00 | Deficiency in Branched Glycosylation in MGAT5 Null or Heterozygous Mice Is Associated with Early-Onset Disease and Increased Severity of Colitis> | 29720442 |
| 2017-12-16 11:36:00 | Study indicates that Mgat5 genotype affects both behaviour and physical outcomes in response to early life stress, suggesting some shared pathways for both in a mouse model. These results provide a starting point for studying the mechanisms by which protein N-glycosylation mediates the effects of early life adversity. | 27329152 |
| 2017-01-14 11:38:00 | Overexpression of GnT-V exacerbated murine experimental colitis by inducing macrophage dysfunction, thereby enhancing colorectal tumorigenesis | 26349931 |
| 2016-05-21 10:26:00 | Expression of GnT-V was also elevated in bleomycin (BLM)-injected sclerotic skin, and MGAT5(-/-) mice were resistant to BLM-induced skin sclerosis with reduced collagen type 1 alpha1 content. | 25876794 |
| 2015-01-24 11:08:00 | GnT-V regulates the canonical Wnt/beta-catenin signaling pathway by modulating N-glycosylation of Wnt receptors, which changes cancer stem cells in colorectal tumors, causing altered colon tumorigenesis and adenoma progression in Apc(min/+) mice | 25274627 |
| Type | IDs |
|---|---|
| Synonymous | 4930471A21Rik, 5330407H02Rik, AI480971, GlcNAc-TV |
| Gene |
UniProtKB-ID:
MGT5A_MOUSE,
Q059T5_MOUSE
UniprotKB:
Q8R4G6,
Q059T5
UniParc:
UPI0000028585
EMBL:
AF474154,
BC125535,
BC125533,
AK030402
Ensembl:
ENSMUSG00000036155
KO:
mmu:107895
|
| Nucleutide sequences |
EMBL-CDS:
AAL83249.1,
BAC26946.1,
AAI25534.1,
AAI25536.1
Ensembl_TRS:
ENSMUST00000171405,
ENSMUST00000038361
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038359,
ENSMUSP00000129166
RefSeq:
XP_006529118.1,
XP_006529120.1,
XP_006529119.1,
XP_030110888.1,
NP_660110.2,
XP_036022125.1
|
| Others |
UniRef100:
UniRef100_Q8R4G6
UniRef90:
UniRef90_Q09328
UniRef50:
UniRef50_Q09328
UniGene:
Mm.214682,
Mm.391592,
Mm.472488
CCDS:
CCDS15245.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员