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107753 Lgals2

107753

Lgals2

lectin, galactose-binding, soluble 2

protein-coding

Mus musculus

基因描述

Type Description
Definition lectin, galactose-binding, soluble 2

研究结论

Date Results Publications
2019-01-19 10:56:00 Galectin-2 (Gal-2) residues near cysteine residues C57 experienced significant chemical shift changes following S-nitrosylation. 29392834
2017-05-06 20:50:00 analysis of the effect of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator 26827730
2017-02-04 12:33:00 Therefore, Cys(57) is suggested to be responsible for oxidative inactivation of the mGal-2 protein, and protection of the sulfhydryl group of the Cys(57) in mGal-2 by S-nitrosylation is likely important for maintaining mGal-2 protein function in an oxidative environment such as the gastrointestinal tract. 27122052
2016-04-16 10:47:00 Studies of specific knock-out mice show that galectin-2 acts through the CD14/toll-like receptor (TLR)-4 pathway. It leads to increased CD40-positive and reduced CD206-positive macrophages around remodeling collateral arteries. 25884209
2015-04-18 11:18:00 Gal-2 oxidation by H2O2 resulted in the loss of sugar-binding ability, while S-nitrosylation prevented H2O2-inducted inactivation, presumably by protecting the Cys residue(s) in the protein. 25619132

名称对应

Type IDs
Synonymous 2200008F12Rik, AI324147
Gene
UniProtKB-ID: LEG2_MOUSE
UniprotKB: Q9CQW5
UniParc: UPI0000029A68
EMBL: AK008648, AK007364, AK008636, AK008423
Ensembl: ENSMUSG00000043501
KO: mmu:107753
Nucleutide sequences
EMBL-CDS: BAB25806.1, BAB24987.1, BAB25661.1, BAB25797.1
Ensembl_TRS: ENSMUST00000044584
Protein sequencees
Ensembl_PRO: ENSMUSP00000036598
RefSeq: NP_079898.2
Others
UniRef100: UniRef100_Q9CQW5
UniRef90: UniRef90_Q9CQW5
UniRef50: UniRef50_Q9Z144
UniGene: Mm.390793
CCDS: CCDS37135.1

全选

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