| Type | Description |
|---|---|
| Definition | polo like kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:29:00 | Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of alpha-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling. | 32192190 |
| 2019-12-28 11:45:00 | There were aberrant expressions of miR-27b and PLK2 in oral lichen planus tissues. Decreased miR-27b may have induced cell proliferation by increasing the levels of PLK2 in oral keratinocytes. | 30638284 |
| 2019-11-16 12:00:00 | In late G1, SIRT1 is hypophosphorylated and its affinity to Plk2 is decreased, resulting in a rapid accumulation of centrosomal Plk2, which contributes to the timely initiation of centriole duplication. | 30517871 |
| 2019-03-16 12:02:00 | The phosphorylation by Plk2, like CDK5, shifts the ratio of GAP activity of synGAP to produce a greater decrease in active Ras than in active Rap, which would produce a shift toward a decrease in the number of surface AMPA receptors in neuronal dendrites. | 30049443 |
| 2018-12-01 11:46:00 | The p53 dependence of Plk2 loss and tumor suppressor function in relationship to mTOR signaling may have therapeutic implications. | 29448085 |
| Type | IDs |
|---|---|
| Synonymous | SNK, hPlk2, hSNK |
| Gene |
UniProtKB-ID:
PLK2_HUMAN,
A0A024QZV1_HUMAN,
A0A087WUH9_HUMAN
UniprotKB:
Q9NYY3,
A0A024QZV1,
A0A087WUH9
UniParc:
UPI0002336B05,
UPI0000135B35
EMBL:
AC008814,
BC013879,
AF223574,
AF059617,
CH471123,
U85755
Ensembl:
ENSG00000145632
KO:
hsa:10769
|
| Nucleutide sequences |
EMBL-CDS:
AAH13879.1,
AAF62897.1,
AAC14573.1,
AAD00575.1,
EAW54973.1,
EAW54972.1
Gene_ORFName:
hCG_39584
Ensembl_TRS:
ENST00000274289,
ENST00000617412
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000274289,
ENSP00000478685
RefSeq:
NP_006613.2,
NP_001239155.1
|
| Others |
UniRef100:
UniRef100_A0A087WUH9,
UniRef100_Q9NYY3
UniRef90:
UniRef90_Q9NYY3
UniRef50:
UniRef50_Q9NYY3
UniGene:
Hs.398157
CCDS:
CCDS3974.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员