| Type | Description |
|---|---|
| Definition | mannan binding lectin serine peptidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:20:00 | Should MASP-2 Deficiency Be Considered a Primary Immunodeficiency? Relevance of the Lectin Pathway. | 31828694 |
| 2020-03-28 12:01:00 | Sporotrichosis patients had decreased levels of MBL and MASP-2 in their serum samples compared with controls. Our findings linked, for the first time, MASP-2 deficiencies with susceptibility to Sporothrix sp. | 31549610 |
| 2020-03-07 10:30:00 | that MASP-2 deficiency can increase susceptibility to adult Herpes simplex virus encephalitis | 31869396 |
| 2019-12-14 12:13:00 | Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors. | 30952698 |
| 2019-09-21 11:27:00 | The allele rs7567833G, the genotypes rs7567833AG and rs7567833GG, and the COLEC11*GGC haplotype were related to T. cruzi infection and clinical progression towards symptomatic Chagas Disease (CD). COLEC11 and MASP2*CD risk genotypes were associated with cardiomyopathy, suggesting that both loci act synergistically in immune modulation of the disease. | 30995222 |
| Type | IDs |
|---|---|
| Synonymous | MAP19, MASP-2, MASP1P1, sMAP |
| Gene |
UniProtKB-ID:
MASP2_HUMAN
UniprotKB:
O00187
UniParc:
UPI000002AD95,
UPI0000161FB9
EMBL:
AL109811,
Y18282,
Y18286,
AB008047,
Y18284,
Y09926,
AF321559,
Y18287,
AF321562,
AJ300188,
AK290823,
AF321560,
AF321558,
AJ297949,
Y18283,
Y18281,
X98400,
AF321561,
AB033742
Ensembl:
ENSG00000009724
KO:
hsa:10747
|
| Nucleutide sequences |
EMBL-CDS:
CAB50731.1,
BAA85659.1,
CAB50734.1,
BAA78616.1,
CAA71059.1,
AAG50274.1,
BAF83512.1,
CAB50732.1,
CAC17139.1,
BAA85658.1,
CAA67050.1,
AAG50275.1,
CAB50728.1,
CAB50735.1,
CAB50730.1,
CAB50733.1,
CAC15568.1,
CAB50729.1,
CAC17138.1
Ensembl_TRS:
ENST00000400898,
ENST00000400897
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383691,
ENSP00000383690
RefSeq:
NP_006601.2,
XP_016855586.1,
NP_631947.1
|
| Others |
UniRef100:
UniRef100_O00187
UniRef90:
UniRef90_O00187
UniRef50:
UniRef50_O00187
UniGene:
Hs.655645
CCDS:
CCDS123.1,
CCDS124.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员