| Type | Description |
|---|---|
| Definition | corin, serine peptidase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | A common CORIN variant in hypertension reduces corin intracellular trafficking by exposing an inhibitory N-terminus. | 32828311 |
| 2020-10-03 12:59:00 | Kruppel-like factor 17 upregulates uterine corin expression and promotes spiral artery remodeling in pregnancy. | 32719113 |
| 2020-09-12 15:57:00 | Sex-specific association between soluble corin and metabolic syndrome in Chinese adults. | 30765878 |
| 2020-05-23 11:01:00 | Study identified potentially functional CORIN SNPs that were associated with serum corin level in the Chinese Han population. The effect of CORIN SNPs on corin level may be mediated by DNA methylation. However, neither SNPs nor serum corin levels was found to be associated with hypertension. | 31856714 |
| 2019-11-23 10:17:00 | Corin plays a unique role in BP regulation throughout normotensive and, especially, hypertensive pregnancy and may represent a promising biomarker for determining women at high risk of adverse pregnancy outcome. | 30580684 |
| Type | IDs |
|---|---|
| Synonymous | ATC2, CRN, Lrp4, PEE5, TMPRSS10 |
| Gene |
UniProtKB-ID:
CORIN_HUMAN,
B4E2W9_HUMAN,
B4E1Y7_HUMAN,
J3KR83_HUMAN,
A0A087X1D5_HUMAN
UniprotKB:
Q9Y5Q5,
B4E2W9,
B4E1Y7,
J3KR83,
A0A087X1D5
UniParc:
UPI00035144FB,
UPI00017A8733,
UPI0001D3B306,
UPI00025F5359,
UPI00017A883C,
UPI0000168657
EMBL:
AK304466,
AC107068,
AF133845,
AK304038,
AF113248,
AC104646,
BC110451,
EU326305,
AC092597
Ensembl:
ENSG00000145244
KO:
hsa:10699
|
| Nucleutide sequences |
EMBL-CDS:
AAI10452.1,
ACA05911.1,
AAY40917.1,
AAY40991.1,
AAF21966.1,
AAD31850.1,
BAG65281.1,
BAG64949.1
Ensembl_TRS:
ENST00000273857,
ENST00000504584,
ENST00000610355
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000273857,
ENSP00000423216,
ENSP00000484087
RefSeq:
NP_001265514.1,
NP_006578.2,
NP_001265515.1
|
| Others |
UniRef100:
UniRef100_B4E1Y7,
UniRef100_B4E2W9,
UniRef100_A0A087X1D5,
UniRef100_Q9Y5Q5,
UniRef100_J3KR83
UniRef90:
UniRef90_A0A087X1D5,
UniRef90_J3KR83,
UniRef90_Q9Y5Q5
UniRef50:
UniRef50_J3KR83,
UniRef50_A0A087X1D5,
UniRef50_Q9Y5Q5
UniGene:
Hs.518618,
Hs.604887
CCDS:
CCDS3477.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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