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10645 CAMKK2

10645

CAMKK2

calcium/calmodulin dependent protein kinase kinase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition calcium/calmodulin dependent protein kinase kinase 2

研究结论

Date Results Publications
2021-03-13 13:18:00 CaMKK2 is inactivated by signaling and 14-3-3 adaptor proteins. 32913128
2021-02-27 13:46:00 Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. 32869834
2021-02-06 13:53:00 Functional analysis of an R311C variant of Ca(2+) -calmodulin-dependent protein kinase kinase-2 (CaMKK2) found as a de novo mutation in a patient with bipolar disorder. 32216002
2020-12-12 13:27:00 Hypomorphic CAMKK2 in EA.hy926 endothelial cells causes abnormal transferrin trafficking, iron homeostasis and glucose metabolism. 32485269
2020-10-24 13:55:00 Polymorphisms in CAMKK2 associate with susceptibility to sensory neuropathy in HIV patients treated without stavudine. 31309408

名称对应

Type IDs
Synonymous CAMKK, CAMKKB
Gene
UniProtKB-ID: KKCC2_HUMAN, A0A024RBQ3_HUMAN, A0A024RBP6_HUMAN, A0A024RBP8_HUMAN, A0A024RBQ0_HUMAN
UniprotKB: Q96RR4, A0A024RBQ3, A0A024RBP6, A0A024RBP8, A0A024RBQ0
UniParc: UPI000013D208, UPI000007477F, UPI00001678BE, UPI0000072CCA, UPI0000074780, UPI0000E59A0E, UPI00000709F0
EMBL: AF321391, AF321386, AF321385, AF321397, CH471054, AB018330, AF321388, BC000318, AF321394, AF091074, AF321395, AF321399, AF287631, AF321396, AB081337, AF321575, AF321398, AF321577, AC069209, AF140507, AF101264, AF321392, AF321400, AF287630, AL834322, AK292072, AF321402, AF321393, AF321576, BC026060, AF321387, AF321401, AB081336, AF321390, AF321578
Ensembl: ENSG00000110931
KO: hsa:10645
Nucleutide sequences
EMBL-CDS: AAL37215.1, BAF84761.1, AAK91830.1, AAL37218.1, AAL37216.1, AAK91829.1, AAK64601.1, AAD04566.1, CAD38990.1, AAC72943.1, AAL37217.1, BAC19841.1, BAA34507.2, AAH26060.1, AAK64600.1, AAH00318.2, AAD31507.1, BAC19840.1, EAW98257.1, EAW98252.1, EAW98248.1, EAW98253.1, EAW98251.1, EAW98250.1, EAW98256.1, EAW98258.1, EAW98254.1
Gene_ORFName: hCG_27364, hCG_27364, hCG_27364, hCG_27364
Ensembl_TRS: ENST00000538733, ENST00000392474, ENST00000404169, ENST00000347034, ENST00000412367, ENST00000446440, ENST00000402834, ENST00000652382, ENST00000337174, ENST00000324774, ENST00000392473
Protein sequencees
Ensembl_PRO: ENSP00000388273, ENSP00000388368, ENSP00000336634, ENSP00000384591, ENSP00000321230, ENSP00000376265, ENSP00000384600, ENSP00000376266, ENSP00000312741, ENSP00000498824, ENSP00000445944
RefSeq: XP_016874195.1, NP_006540.3, NP_757363.1, XP_016874197.1, XP_016874194.1, NP_757365.1, XP_016874184.1, NP_705720.1, XP_016874189.1, XP_016874191.1, XP_011536065.1, NP_001257414.1, XP_016874188.1, NP_705719.2, XP_016874183.1, XP_005253880.1, XP_011536066.1, XP_005253879.1, NP_001257415.1, XP_016874192.1, XP_024304566.1, NP_757380.1, XP_016874198.1, XP_005253881.1, NP_757364.1, XP_024304567.1
Others
UniRef100: UniRef100_A0A024RBP6, UniRef100_Q96RR4, UniRef100_A0A024RBP8, UniRef100_A0A024RBQ3
UniRef90: UniRef90_A0A024RBQ3, UniRef90_Q96RR4, UniRef90_Q96RR4-7
UniRef50: UniRef50_Q96RR4, UniRef50_Q96RR4-7
UniGene: Hs.297343
CCDS: CCDS53837.1, CCDS9218.1, CCDS9217.1, CCDS58283.1, CCDS44999.1, CCDS9219.1, CCDS9216.1

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