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106298 Rrn3

106298

Rrn3

RRN3 RNA polymerase I transcription factor homolog (yeast)

protein-coding

Mus musculus

基因描述

Type Description
Definition RRN3 RNA polymerase I transcription factor homolog (yeast)

研究结论

Date Results Publications
2017-08-26 11:08:00 Conditional deletion of the Rrn3 gene inhibits RNA polymerase I transcription but does not affect pre-initiation complex formation. 28715449
2017-06-24 10:31:00 The results exemplify how stress-induced inactivation of TIF-IA and long non-coding RNA -dependent changes of chromatin structure ensure repression of ribosomal RNA synthesis in response to thermo-stress. 27257073
2014-03-01 11:50:00 These data support a model in which activated Akt enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA. 24297901
2013-06-01 12:02:00 DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription 23393135
2013-01-07 11:42:00 Ablation of TIF-IA leads to impaired nucleolar activity and results in increased levels of the proapoptotic transcription factor p53 in both neural progenitors and hippocampal neurons but induces rapid apoptosis only in neural progenitors. 19036968

名称对应

Type IDs
Synonymous AL023001, E130302O19Rik, R75565, TIF-1A, Tif1a
Gene
UniProtKB-ID: RRN3_MOUSE
UniprotKB: B2RS91
UniParc: UPI00001C5AA1
EMBL: BC034110, BC055781, BC138774, BC138776
Ensembl: ENSMUSG00000022682
KO: mmu:106298
Nucleutide sequences
EMBL-CDS: AAH34110.1, AAI38775.1, AAI38777.1, AAH55781.1
Ensembl_TRS: ENSMUST00000023363
Protein sequencees
Ensembl_PRO: ENSMUSP00000023363
RefSeq: XP_036015620.1, NP_001034610.1
Others
UniRef100: UniRef100_B2RS91
UniRef90: UniRef90_B2RS91
UniRef50: UniRef50_B2RS91
UniGene: Mm.490362
CCDS: CCDS27968.1

全选

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研究热度

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