| Type | Description |
|---|---|
| Definition | CDC42 effector protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:27:00 | Overactivated Cdc42 acts through Cdc42EP3/Borg2 and NCK to trigger DNA damage response signaling and sensitize cells to DNA-damaging agents. | 32739212 |
| 2017-11-11 13:39:00 | Results provide evidence that Cdc42EP3 function in cancer-associated fibroblasts relies on tight regulation by Cdc42. | 27248291 |
| 2017-07-22 11:16:00 | Studies indicate some of the functional and mechanistic roles of the binder of Rho GTPases Borg1-5 proteins (Cdc42EP1-5), including cytoskeletal remodelling and signalling. | 27913681 |
| 2010-10-23 10:23:00 | The expression of CDC42EP3 mRNA was significantly increased by 19.7% in dorsal prefrontal cortex in patient with schizophrenia. | 20385374 |
| Type | IDs |
|---|---|
| Synonymous | BORG2, CEP3, UB1 |
| Gene |
UniProtKB-ID:
BORG2_HUMAN
UniprotKB:
Q9UKI2
UniParc:
UPI0000073D2A
EMBL:
AF094521,
AF104857,
BT007190,
AL136842,
CH471053,
AK313483,
AF164118,
AC006369,
BC019270
Ensembl:
ENSG00000163171
KO:
hsa:10602
|
| Nucleutide sequences |
EMBL-CDS:
AAX93072.1,
AAD16888.1,
AAD48815.1,
AAH19270.1,
AAP35854.1,
EAX00390.1,
CAB66776.1,
BAG36267.1,
AAC71773.1
Ensembl_TRS:
ENST00000295324,
ENST00000611976
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000480549,
ENSP00000295324
RefSeq:
NP_006440.2,
NP_001257365.1,
XP_011530784.1,
NP_001358498.1,
NP_001257367.1,
NP_001257366.1,
NP_001358499.1
|
| Others |
UniRef100:
UniRef100_Q9UKI2
UniRef90:
UniRef90_Q9UKI2
UniRef50:
UniRef50_Q9UKI2
UniGene:
Hs.369574
CCDS:
CCDS1791.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32739212 |
Exp Cell Res Luiz Eduardo da Silva , Lilian Cristina Russo , Fabio Luis Forti |
2020-10-15 | - |
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31478661 |
J. Proteome Res. Luiz E Silva , Renan C Souza , Eduardo S Kitano , Lucas F Monteiro , Leo K Iwai , Fabio L Forti |
2019-10-04 | - |
| 29513927 |
Proteomics James E Tomkins , Sybille Dihanich , Alexandra Beilina , Raffaele Ferrari , Nicolò Ilacqua , Mark R Cookson , Patrick A Lewis , Claudia Manzoni |
2018-05-01 | - |
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 27248291 |
Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts. Small GTPases Aaron J Farrugia , Fernando Calvo |
2017-01-02 | - |
| 27913681 |
The Borg family of Cdc42 effector proteins Cdc42EP1-5. Biochem Soc Trans Aaron J Farrugia , Fernando Calvo |
2016-12-15 | - |
| 24947832 |
J. Neurochem. Lauran Reyniers , Maria Grazia Del Giudice , Laura Civiero , Elisa Belluzzi , Evy Lobbestael , Alexandra Beilina , Giorgio Arrigoni , Rita Derua , Etienne Waelkens , Yan Li , Claudia Crosio , Ciro Iaccarino , Mark R Cookson , Veerle Baekelandt , Elisa Greggio , Jean-Marc Taymans |
2014-10-01 | - |
| 23563607 |
Nat. Genet. Sonja I Berndt , Stefan Gustafsson , Reedik Mägi , Andrea Ganna , Eleanor Wheeler , Mary F Feitosa , Anne E Justice , Keri L Monda , Damien C Croteau-Chonka , Felix R Day , Tõnu Esko , Tove Fall , Teresa Ferreira , Davide Gentilini , Anne U Jackson , Jian'an Luan , Joshua C Randall , Sailaja Vedantam , Cristen J Willer , Thomas W Winkler , Andrew R Wood , Tsegaselassie Workalemahu , Yi-Juan Hu , Sang Hong Lee , Liming Liang , Dan-Yu Lin , Josine L Min , Benjamin M Neale , Gudmar Thorleifsson , Jian Yang , Eva Albrecht , Najaf Amin , Jennifer L Bragg-Gresham , Gemma Cadby , Martin den Heijer , Niina Eklund , Krista Fischer , Anuj Goel , Jouke-Jan Hottenga , Jennifer E Huffman , Ivonne Jarick , à sa Johansson , Toby Johnson , Stavroula Kanoni , Marcus E Kleber , Inke R König , Kati Kristiansson , Zoltán Kutalik , Claudia Lamina , Cecile Lecoeur , Guo Li , Massimo Mangino , Wendy L McArdle , Carolina Medina-Gomez , Martina Müller-Nurasyid , Julius S Ngwa , Ilja M Nolte , Lavinia Paternoster , Sonali Pechlivanis , Markus Perola , Marjolein J Peters , Michael Preuss , Lynda M Rose , Jianxin Shi , Dmitry Shungin , Albert Vernon Smith , Rona J Strawbridge , Ida Surakka , Alexander Teumer , Mieke D Trip , Jonathan Tyrer , Jana V Van Vliet-Ostaptchouk , Liesbeth Vandenput , Lindsay L Waite , Jing Hua Zhao , Devin Absher , Folkert W Asselbergs , Mustafa Atalay , Antony P Attwood , Anthony J Balmforth , Hanneke Basart , John Beilby , Lori L Bonnycastle , Paolo Brambilla , Marcel Bruinenberg , Harry Campbell , Daniel I Chasman , Peter S Chines , Francis S Collins , John M Connell , William O Cookson , Ulf de Faire , Femmie de Vegt , Mariano Dei , Maria Dimitriou , Sarah Edkins , Karol Estrada , David M Evans , Martin Farrall , Marco M Ferrario , Jean Ferrières , Lude Franke , Francesca Frau , Pablo V Gejman , Harald Grallert , Henrik Grönberg , Vilmundur Gudnason , Alistair S Hall , Per Hall , Anna-Liisa Hartikainen , Caroline Hayward , Nancy L Heard-Costa , Andrew C Heath , Johannes Hebebrand , Georg Homuth , Frank B Hu , Sarah E Hunt , Elina Hyppönen , Carlos Iribarren , Kevin B Jacobs , John-Olov Jansson , Antti Jula , Mika Kähönen , Sekar Kathiresan , Frank Kee , Kay-Tee Khaw , Mika Kivimäki , Wolfgang Koenig , Aldi T Kraja , Meena Kumari , Kari Kuulasmaa , Johanna Kuusisto , Jaana H Laitinen , Timo A Lakka , Claudia Langenberg , Lenore J Launer , Lars Lind , Jaana Lindström , Jianjun Liu , Antonio Liuzzi , Marja-Liisa Lokki , Mattias Lorentzon , Pamela A Madden , Patrik K Magnusson , Paolo Manunta , Diana Marek , Winfried März , Irene Mateo Leach , Barbara McKnight , Sarah E Medland , Evelin Mihailov , Lili Milani , Grant W Montgomery , Vincent Mooser , Thomas W Mühleisen , Patricia B Munroe , Arthur W Musk , Narisu Narisu , Gerjan Navis , George Nicholson , Ellen A Nohr , Ken K Ong , Ben A Oostra , Colin N A Palmer , Aarno Palotie , John F Peden , Nancy Pedersen , Annette Peters , Ozren Polasek , Anneli Pouta , Peter P Pramstaller , Inga Prokopenko , Carolin Pütter , Aparna Radhakrishnan , Olli Raitakari , Augusto Rendon , Fernando Rivadeneira , Igor Rudan , Timo E Saaristo , Jennifer G Sambrook , Alan R Sanders , Serena Sanna , Jouko Saramies , Sabine Schipf , Stefan Schreiber , Heribert Schunkert , So-Youn Shin , Stefano Signorini , Juha Sinisalo , Boris Skrobek , Nicole Soranzo , Alena StanÄáková , Klaus Stark , Jonathan C Stephens , Kathleen Stirrups , Ronald P Stolk , Michael Stumvoll , Amy J Swift , Eirini V Theodoraki , Barbara Thorand , David-Alexandre Tregouet , Elena Tremoli , Melanie M Van der Klauw , Joyce B J van Meurs , Sita H Vermeulen , Jorma Viikari , Jarmo Virtamo , Veronique Vitart , Gérard Waeber , Zhaoming Wang , Elisabeth Widén , Sarah H Wild , Gonneke Willemsen , Bernhard R Winkelmann , Jacqueline C M Witteman , Bruce H R Wolffenbuttel , Andrew Wong , Alan F Wright , M Carola Zillikens , Philippe Amouyel , Bernhard O Boehm , Eric Boerwinkle , Dorret I Boomsma , Mark J Caulfield , Stephen J Chanock , L Adrienne Cupples , Daniele Cusi , George V Dedoussis , Jeanette Erdmann , Johan G Eriksson , Paul W Franks , Philippe Froguel , Christian Gieger , Ulf Gyllensten , Anders Hamsten , Tamara B Harris , Christian Hengstenberg , Andrew A Hicks , Aroon Hingorani , Anke Hinney , Albert Hofman , Kees G Hovingh , Kristian Hveem , Thomas Illig , Marjo-Riitta Jarvelin , Karl-Heinz Jöckel , Sirkka M Keinanen-Kiukaanniemi , Lambertus A Kiemeney , Diana Kuh , Markku Laakso , Terho Lehtimäki , Douglas F Levinson , Nicholas G Martin , Andres Metspalu , Andrew D Morris , Markku S Nieminen , Inger Njølstad , Claes Ohlsson , Albertine J Oldehinkel , Willem H Ouwehand , Lyle J Palmer , Brenda Penninx , Chris Power , Michael A Province , Bruce M Psaty , Lu Qi , Rainer Rauramaa , Paul M Ridker , Samuli Ripatti , Veikko Salomaa , Nilesh J Samani , Harold Snieder , Thorkild I A Sørensen , Timothy D Spector , Kari Stefansson , Anke Tönjes , Jaakko Tuomilehto , André G Uitterlinden , Matti Uusitupa , Pim van der Harst , Peter Vollenweider , Henri Wallaschofski , Nicholas J Wareham , Hugh Watkins , H-Erich Wichmann , James F Wilson , Goncalo R Abecasis , Themistocles L Assimes , Inês Barroso , Michael Boehnke , Ingrid B Borecki , Panos Deloukas , Caroline S Fox , Timothy Frayling , Leif C Groop , Talin Haritunian , Iris M Heid , David Hunter , Robert C Kaplan , Fredrik Karpe , Miriam F Moffatt , Karen L Mohlke , Jeffrey R O'Connell , Yudi Pawitan , Eric E Schadt , David Schlessinger , Valgerdur Steinthorsdottir , David P Strachan , Unnur Thorsteinsdottir , Cornelia M van Duijn , Peter M Visscher , Anna Maria Di Blasio , Joel N Hirschhorn , Cecilia M Lindgren , Andrew P Morris , David Meyre , André Scherag , Mark I McCarthy , Elizabeth K Speliotes , Kari E North , Ruth J F Loos , Erik Ingelsson |
2013-05-01 | - |
| 23602568 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep Markku Varjosalo , Salla Keskitalo , Audrey Van Drogen , Helka Nurkkala , Anton Vichalkovski , Ruedi Aebersold , Matthias Gstaiger |
2013-04-25 |
MED6,
PDCD6IP,
FRAT1,
TROAP,
MED16,
RWDD2B,
HUWE1,
EDIL3,
ARPC1B,
HIPK3,
FRY,
AKAP9,
SUGP2,
RASA4,
CDK2,
RBM7,
CDK3,
CDK4,
PSME3,
CDK5,
FLOT1,
DDX39A,
CDK6,
CDK7,
HNRNPR,
DCAF7,
CDK8,
SRRM1,
CDK9,
SF3B4,
CDKN1A,
AKAP8,
CDKN1B,
STUB1,
CDKN1C,
CDKN2A,
PAK4,
CDKN2B,
ZNF267,
CDKN2C,
CDKN2D,
NPM2,
CACNG2,
RBM14,
HAX1,
BAIAP2,
PFDN6,
EIF3M,
SEC23B,
ENOX2,
MYBBP1A,
CHERP,
NOP56,
UBD,
MAB21L2,
DRAP1,
PRPF8,
CDC42EP3,
USP39,
PTGES3,
YME1L1,
NUP50,
HBS1L,
AHCYL1,
ZMYND11,
ZNF460,
CPSF4,
TRAFD1,
MAGED2,
RNPS1,
SUB1,
SRSF8,
AFG3L2,
MSL3,
STIP1,
EBNA1BP2,
SNRNP27,
STON1,
NUDT21,
CPSF6,
CHD2,
SNRNP35,
DIDO1,
WDR5,
KRR1,
FOXN3,
CLASRP,
KPTN,
WDR6,
SUPT16H,
CHEK2,
AKAP11,
EGLN2,
MED8,
GLCCI1,
GABARAP,
U2AF2,
CHUK,
EVI5L
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员