| Type | Description |
|---|---|
| Definition | mastermind like transcriptional coactivator 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:06:00 | microRNA-193b protects against myocardial ischemia-reperfusion injury in mouse by targeting mastermind-like 1. | 30993760 |
| 2020-02-22 10:45:00 | dnMAML1 expression leads to robust precocious oligodendrocytes differentiation and premature axonal myelination in the spinal cord, possibly by upregulating Nkx2.2 and downregulating Pdgfra expression. Unexpectedly, at late embryonic stages, dnMAML1 expression dramatically increased the number of oligodendrocyte precursor cells (OPCs), indicating a stage-dependent effect of Notch signaling on OPC proliferation. | 31038233 |
| 2020-02-08 10:38:00 | Neuron production in mouse cerebral cortex is coordinated by the MAML1. | 31416089 |
| 2018-04-07 11:51:00 | The present study shows a new role for Maml1 as a component of Shh signaling, which plays a crucial role in both development and tumorigenesis. | 28726779 |
| 2017-05-13 21:50:00 | Similar phenotypes were observed by conditionally misexpressing a dominant negative form of MAML1 in Mitral cells ( MCs)after their migration. Furthermore, the intracellular domain of Notch1 (NICD1) was localized to nuclei of MCs. These findings suggest that Notch signaling at embryonic stages is involved in the dendritic complexity of MCs | 28027303 |
| Type | IDs |
|---|---|
| Synonymous | AI644666, AW743257, D930008C07Rik, Mam-1, Mam1, mKIAA0200 |
| Gene |
UniProtKB-ID:
MAML1_MOUSE
UniprotKB:
Q6T264
UniParc:
UPI000053E853
EMBL:
AK086146,
BC094599,
AL646002,
AK129088,
BC024668,
BC058658,
AY442299
Ensembl:
ENSMUSG00000050567
KO:
mmu:103806
|
| Nucleutide sequences |
EMBL-CDS:
AAH58658.1,
AAH24668.1,
AAS07633.1,
BAC97898.1,
AAH94599.2,
BAC39618.1
Ensembl_TRS:
ENSMUST00000059458
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059210
RefSeq:
NP_780543.2,
XP_006531981.1
|
| Others |
UniRef100:
UniRef100_Q6T264
UniRef90:
UniRef90_Q6T264
UniRef50:
UniRef50_Q6T264
UniGene:
Mm.51116
CCDS:
CCDS24632.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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