| Type | Description |
|---|---|
| Definition | TRK-fused gene |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 12:59:00 | Tropomyosin-receptor kinase fused gene (TFG) regulates lipid production in human sebocytes. | 31036933 |
| 2020-08-12 14:53:00 | Continuum of phenotypes in hereditary motor and sensory neuropathy with proximal predominance and Charcot-Marie-Tooth patients with TFG mutation has been described. | 31111683 |
| 2020-02-01 10:31:00 | Data highlight a key role for TFG-mediated protein transport in the pathogenesis of HSP. | 30157421 |
| 2019-09-28 11:19:00 | This study highlights phenotypic heterogeneity characterizing individuals carrying the same pathogenic variant in TFG and provides an insight on tight connection linking mitochondrial efficiency and neuronal health to vesicular trafficking. | 29971521 |
| 2019-06-08 12:41:00 | Study suggests that a genetic variant in an intron of TFG may be associated with skin aging in Korean females, and TFG may be an interesting new candidate gene for exploring individual differences in the molecular bases of collagen and MMP production. | 28882477 |
| Type | IDs |
|---|---|
| Synonymous | HMSNP, SPG57, TF6, TRKT3 |
| Gene |
UniProtKB-ID:
TFG_HUMAN,
Q05BK6_HUMAN
UniprotKB:
Q92734,
Q05BK6
UniParc:
UPI00028B1A6F,
UPI00028BC20B,
UPI0000D4A72F,
UPI0000E5747E,
UPI0000073CDE
EMBL:
BC023599,
KF457659,
AB731570,
BT007428,
KF457666,
BC001483,
AC068763,
CR456781,
X85960,
BC041600,
CH471052,
AB731569,
Y07968,
AK093456,
BC009241
Ensembl:
ENSG00000114354
KO:
hsa:10342
|
| Nucleutide sequences |
EMBL-CDS:
CAG33062.1,
CAA69264.1,
EAW79813.1,
EAW79815.1,
AAP36096.1,
CAA59936.1,
BAM48927.1,
AAH23599.1,
EAW79817.1,
EAW79816.1,
BAG52721.1,
AAH01483.1,
EAW79814.1,
AAH09241.1,
BAM48926.1,
AAH41600.1
Ensembl_TRS:
ENST00000476228,
ENST00000240851,
ENST00000615993,
ENST00000490574,
ENST00000418917,
ENST00000620299
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000397182,
ENSP00000479269,
ENSP00000419960,
ENSP00000417952,
ENSP00000479981,
ENSP00000240851
RefSeq:
NP_006061.2,
NP_001182407.1,
XP_005247123.1,
NP_001007566.1,
NP_001182408.1,
XP_016861016.1,
XP_006713535.1,
XP_011510636.1
|
| Others |
UniRef100:
UniRef100_Q05BK6,
UniRef100_Q92734
UniRef90:
UniRef90_Q05BK6,
UniRef90_Q92734
UniRef50:
UniRef50_Q92734,
UniRef50_G1KLC4
UniGene:
Hs.518123
CCDS:
CCDS56266.1,
CCDS2939.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员