| Type | Description |
|---|---|
| Definition | actin related protein 2/3 complex subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 10:51:00 | Study provides evidence that the 5'-UTR1 of has internal ribosome entry site activity and regulates translation during stressful cellular conditions such as high cell density. | 31387452 |
| 2019-08-17 11:38:00 | Results find that expression is upregulated in breast cancer tissues and cell lines. duanyu37C2 promotes the proliferation and metastasis of human breast cancer cells. duanyu37C2 is regulated by RBM2 in a posttranscriptional 3'UTRbinding manner. Also, duanyu37C2 plays an oncogenic role and mediates the promoting role of RBM3 in the proliferation and metastasis of human breast cancer cells. | 30720048 |
| 2019-08-17 10:51:00 | These results collectively indicated that promoted the tumorigenesis of breast carcinoma and the initiation of epithelialmesenchymal transition. Therefore, duanyu37C2 was revealed to be a potential therapeutic target in patients with breast cancer (BrCa) . | 31002363 |
| 2019-04-06 12:45:00 | Study shows that the T-cell-specific deletion of Arpc2 results in compromised peripheral T-cell homeostasis suggesting that is essential for T-cell homeostasis probably by maintaining surface TCR levels via regulating TCR(+) endosome trafficking. | 28827576 |
| 2018-05-05 11:30:00 | In the association analysis of 110 gastric cancer tissues, showed significant associations with large tumor size, lymph node invasion, and high tumor stage. In addition, patients exhibited lower RFS and OS rates compared with patients. We thus identify that duanyu37C2 plays an aneretic role in human gastric cancer and provided a new target for gastric cancer therapy. | 28694563 |
| Type | IDs |
|---|---|
| Synonymous | ARC34, PNAS-139, PRO2446, p34-Arc |
| Gene |
UniProtKB-ID:
ARPC2_HUMAN,
Q53R19_HUMAN,
A0A024R408_HUMAN
UniprotKB:
O15144,
Q53R19,
A0A024R408
UniParc:
UPI000020957E,
UPI0000125D3D
EMBL:
AK290268,
AC097483,
U50523,
AF116702,
HM005676,
CH471063,
BT006898,
AF006085,
BC000590
Ensembl:
ENSG00000163466
KO:
hsa:10109
|
| Nucleutide sequences |
EMBL-CDS:
AAF71122.1,
AAC50874.1,
AAP35544.1,
AAB64190.1,
AAH00590.1,
AAX93213.1,
BAF82957.1,
EAW70591.1,
EAW70593.1,
AEE61273.1,
EAW70597.1,
EAW70592.1
Gene_ORFName:
PRO2446,
hCG_16304,
hCG_16304
Ensembl_TRS:
ENST00000295685,
ENST00000315717
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000327137,
ENSP00000295685
RefSeq:
XP_016858603.1,
NP_690601.1,
XP_016858602.1,
XP_016858604.1,
NP_005722.1,
XP_024308277.1
|
| Others |
UniRef100:
UniRef100_O15144
UniRef90:
UniRef90_O15144
UniRef50:
UniRef50_O15144
UniGene:
Hs.529303
CCDS:
CCDS2410.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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