| Type | Description |
|---|---|
| Definition | snurportin 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-11-05 11:04:00 | Results show that marker rs218966 in gene PHF14 and rs9836027 in MAP4 significantly associated with hypertension; additionally, rare variants in SNUPN significantly associated with systolic blood pressure. | 26866982 |
| 2015-01-17 10:15:00 | analysis of interactions between CRM1 and the nuclear pore protein Tpr and snurportin | 24722547 |
| 2010-01-21 00:00:00 | SPN construct lacking the importin beta binding domain (IBB) localizes primarily to the nucleus rather than to the cytoplasm. | 12095920 |
| 2010-01-21 00:00:00 | There is an interaction between the N- and C-terminal domains of SPN, suggesting an autoregulatory function similar to that of importin-alpha. | 16030253 |
| 2010-01-21 00:00:00 | study presents the crystal structure of the SPN1.CRM1.RanGTP export complex at 2.5 angstrom resolution (where SPN1 is snurportin1 and RanGTP is guanosine 5' triphosphate-bound Ran | 19389996 |
| Type | IDs |
|---|---|
| Synonymous | KPNBL, RNUT1, Snurportin1 |
| Gene |
UniProtKB-ID:
SPN1_HUMAN
UniprotKB:
O95149
UniParc:
UPI0000031A89
EMBL:
CH471136,
AF039029,
BC004203,
AK289475,
CR456811
Ensembl:
ENSG00000169371
KO:
hsa:10073
|
| Nucleutide sequences |
EMBL-CDS:
EAW99245.1,
BAF82164.1,
CAG33092.1,
AAC70906.1,
AAH04203.1,
EAW99246.1
Ensembl_TRS:
ENST00000564644,
ENST00000567134,
ENST00000308588,
ENST00000564675
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000458053,
ENSP00000456224,
ENSP00000454852,
ENSP00000309831
RefSeq:
NP_001036046.1,
NP_005692.1,
NP_001036053.1
|
| Others |
UniRef100:
UniRef100_O95149
UniRef90:
UniRef90_O95149
UniRef50:
UniRef50_O95149
UniGene:
Hs.21577
CCDS:
CCDS10281.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30021884 |
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck |
2018-10-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26866982 |
Filtering genetic variants and placing informative priors based on putative biological function. BMC Genet. Stefanie Friedrichs , Dörthe Malzahn , Elizabeth W Pugh , Marcio Almeida , Xiao Qing Liu , Julia N Bailey |
2016-02-03 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 26344197 |
Panorama of ancient metazoan macromolecular complexes. Nature Cuihong Wan , Blake Borgeson , Sadhna Phanse , Fan Tu , Kevin Drew , Greg Clark , Xuejian Xiong , Olga Kagan , Julian Kwan , Alexandr Bezginov , Kyle Chessman , Swati Pal , Graham Cromar , Ophelia Papoulas , Zuyao Ni , Daniel R Boutz , Snejana Stoilova , Pierre C Havugimana , Xinghua Guo , Ramy H Malty , Mihail Sarov , Jack Greenblatt , Mohan Babu , W Brent Derry , Elisabeth R Tillier , John B Wallingford , John Parkinson , Edward M Marcotte , Andrew Emili |
2015-09-17 |
AKT3,
MED6,
ABI1,
GNPDA1,
SRA1,
TDRD15,
HMGN1P30,
PDCD6IP,
PDCD6,
MED16,
ADA,
CHAF1A,
TOM1,
RANBP9,
SMC4,
ARPC4-TTLL3,
RBM14-RBM4,
RNF103-CHMP3,
CHURC1-FNTB,
AP1M2,
ISY1-RAB43,
UBA2,
SAE1,
FARSB,
DNM1L,
ABCF2,
COX17,
SCAMP2,
SCAMP3,
DPP3,
SNUPN,
HUWE1,
TSSC4,
ATP9A,
PQBP1,
COL4A3BP,
PTGES3L-AARSD1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
PPIF,
LOC101060521,
ARPC2,
RAD50,
ACTR1B,
ACTR1A,
ADAM8,
LRPPRC,
PDIA6,
TRAP1,
BCAP31,
NAMPT,
RBM12,
G3BP1,
ABI2,
CEBPZ,
TRIM28,
AASS,
ATP6AP2,
WASF2,
SLC25A13,
CDK2,
RBM7,
ALYREF,
TXNDC9,
LOC101929876,
PSME3,
MPHOSPH10,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
DDX39A,
PSMD14,
CDK7,
PLIN3,
HNRNPR,
MRPS31,
CDK8,
RABEPK,
RIDA,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
AKAP8,
STUB1,
STAG1,
UBE4B,
PRSS16,
SIGMAR1,
BET1,
CWC27,
SAP18
|
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 24722547 |
The interaction of CRM1 and the nuclear pore protein Tpr. PLoS ONE Charles L Zhao , Seyed Hanif Mahboobi , Ruhollah Moussavi-Baygi , Mohammad R K Mofrad |
2014-01-01 |
SNUPN,
TPR,
XPO1
|
| 23850451 |
Structural determinants and mechanism of mammalian CRM1 allostery. Structure Nicole Dölker , Clement E Blanchet , Béla Voà , David Haselbach , Christian Kappel , Thomas Monecke , Dmitri I Svergun , Holger Stark , Ralf Ficner , Ulrich Zachariae , Helmut Grubmüller , Achim Dickmanns |
2013-08-06 |
XPO1
|
| 23376485 |
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. J Proteomics Marco Prunotto , Annarita Farina , Lydie Lane , Agnès Pernin , Jürg Schifferli , Denis F Hochstrasser , Pierre Lescuyer , Solange Moll |
2013-04-26 |
CDH2,
GNPDA1,
C1orf68,
PDCD6IP,
PDCD6,
TOM1L1,
CDH6,
IL18BP,
DPP3,
SNUPN,
ARPC5,
CDH11,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
TSPAN1,
ARPC2,
ACTR1B,
ACTR1A,
CDH13,
PDIA6,
TRAP1,
PDZK1IP1,
ATP6AP2,
DHRS2,
NUTF2,
FLOT1,
PSMD14,
RIDA,
GLYAT,
ZMPSTE24,
STUB1,
RTN3,
LANCL1,
CRISP3,
SIRPB1,
AKR1A1,
TFG,
TUBA1B,
BPNT1,
TUBB4B,
BTN2A2,
NDRG1,
RACK1,
ST3GAL6,
CPQ,
WFDC2,
BASP1,
IFITM3,
CDSN,
LYPLA1,
FAM3C,
ACAA2,
VAV3,
TOMM40,
BAIAP2,
ATP5H,
CEACAM5,
CAP1,
VAT1,
FBLN5,
CIB1,
GLRX3,
PROCR,
ARL6IP5,
ARPC1A,
OLFM4,
CEL,
CCT7,
CCT4,
CCT2,
NPC2,
DNPH1,
PAICS,
MYL12A,
ATP5L,
YKT6,
PMVK,
GNA13,
B3GNT2,
CCT8,
CETP,
CFL1,
PTGES3,
RBBP9,
MASP2,
CTSC,
GIPC1,
AHCYL1,
IQGAP2,
VAMP5,
CFTR,
ALDH1L1,
FTCD,
RUVBL2,
PGRMC1,
FGL2
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员