| Type | Description |
|---|---|
| Definition | low density lipoprotein receptor adaptor protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 14:40:00 | The combination of Arh and Dab2 is responsible for the majority of adaptor function in LDLR endocytosis and LDLR-mediated cholesterol homeostasis. | 27005486 |
| 2013-11-02 10:58:00 | cells that depend upon ARH for LDL uptake can control which lipoproteins are internalized by their LDLRs through changes in nitric oxide. | 23564733 |
| 2010-01-21 00:00:00 | results are consistent with LDL receptor adaptor protein(ARH) playing a critical and specific role in low density lipoprotein receptor endocytosis in the liver | 12746448 |
| 2010-01-21 00:00:00 | the LDL receptor alone can account for the clearance of apoE-containing lipoproteins in mice, and the contribution of other receptors is minimal, and b) defects in either increase the sensitivity to apoE-induced hypertriglyceridemia in mice. | 16339113 |
| 2010-01-21 00:00:00 | Hepatocytes do not take-up LDL in vivo without ARH protein, but they normally catabolize LDL in vitro. Thus, the requirement of ARH protein for proper functioning of the LDLR is not cell-specific, but rather may depend on the cellular environment. | 15472122 |
| Type | IDs |
|---|---|
| Synonymous | AA691260, ARH2, Arh, Arh1, FHCB1, FHCB2 |
| Gene |
UniProtKB-ID:
ARH_MOUSE
UniprotKB:
Q8C142
UniParc:
UPI0000155512
EMBL:
BC066808,
AL645531,
AK167290,
CH466552,
AK029008,
BC067411,
AK148340,
BC021467,
AK159800
Ensembl:
ENSMUSG00000037295
KO:
mmu:100017
|
| Nucleutide sequences |
EMBL-CDS:
AAH66808.1,
BAE39396.1,
BAE28493.1,
BAE35380.1,
AAH21467.1,
AAH67411.1,
BAC26238.1,
EDL30001.1
Ensembl_TRS:
ENSMUST00000037828
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036749
RefSeq:
NP_663529.2,
XP_006538486.1
|
| Others |
UniRef100:
UniRef100_Q8C142
UniRef90:
UniRef90_Q8C142
UniRef50:
UniRef50_Q8C142
UniGene:
Mm.482148
CCDS:
CCDS51327.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员