| Type | Description |
|---|---|
| Definition | ryanodine receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 12:29:00 | Findings revealed that Ca2+ influx through L-type Ca(2+) channels (LTCCs) provides the immediate and efficient Ca2+ microdomain for the activation of SK channels. SK channel activation is predicted to provide a feedback mechanism to regulate the activities of LTCCs and RyR2 to influence the local and global Ca2+ signaling through the effects of SK channels on membrane potentials. | 29549309 |
| 2018-01-06 11:56:00 | Study determined the three-dimensional structure of rabbit RyR2 in complex with the regulatory protein FKBP12.6 in the closed state at 11.8 A resolution using cryo-electron microscopy and built an atomic model of RyR2. | 28536302 |
| 2014-04-26 11:40:00 | Two regions of the ryanodine receptor calcium channel are involved in Ca(2+)-dependent inactivation | 24521037 |
| 2013-02-02 10:54:00 | [REVIEW] The efficacy of divalent calcium ion (Ca2+) release in the myocardium depends on the amount of Ca2+ loaded into the Ca2+ store and the way in which this Ca2* load influences the activity of the ryanodine receptor Ca2+ release channel (RyR2). | 22524859 |
| 2012-11-03 10:11:00 | There were substantial transmural gradients in Cav1.2, KChIP2, ERG, KvLQT1, Kir2.1, NCX1, SERCA2a and RyR2 at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium. | 22537893 |
| Type | IDs |
|---|---|
| Synonymous | RYR-2 |
| Gene |
UniProtKB-ID:
Q29621_RABIT
UniprotKB:
Q29621
UniParc:
UPI00001101BF
EMBL:
U50465
KO:
ocu:100009536
|
| Nucleutide sequences |
EMBL-CDS:
AAA93465.1
|
| Protein sequencees |
RefSeq:
NP_001076226.1
|
| Others |
UniRef100:
UniRef100_Q29621
UniRef90:
UniRef90_Q92736
UniRef50:
UniRef50_Q92736
UniGene:
Ocu.1832
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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