The CW domain, a structural module shared amongst vertebrates, vertebrate-infecting parasites and higher plants.

Trends Biochem. Sci.2003 Nov;28(11):576-80

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A previously undetected domain, named CW for its conserved cysteine and tryptophan residues, appears to be a four-cysteine zinc-finger motif found exclusively in vertebrates, vertebrate-infecting parasites and higher plants. Of the twelve distinct nuclear protein families that comprise the CW domain-containing superfamily, only the microrchida (MORC) family has begun to be characterized. However, several families contain other domains suggesting a relationship between the CW domain and either chromatin methylation status or early embryonic development.

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The CW domain, a structural module shared amongst vertebrates, vertebrate-infecting parasites and higher plants.

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