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22880 MORC2

22880

MORC2

MORC family CW-type zinc finger 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition MORC family CW-type zinc finger 2

研究结论

Date Results Publications
2020-10-24 14:10:00 Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism. 32693025
2020-10-03 12:50:00 MORC2 regulates C/EBPalpha-mediated cell differentiation via sumoylation. 30644437
2020-10-03 12:12:00 The MORC2 can form a homodimer through its C-terminal coiled-coil (CC) domain, a process that is enhanced in response to chemotherapeutic drug camptothecin-induced DNA damage. 31796101
2020-07-18 11:38:00 the findings of this study demonstrated the oncogenic role of MORC2 in cholangiocarcinoma tumorigenesis and metastasis, and clarified an underlying regulatory mechanism mediating MORC2 upregulation 31180332
2020-07-11 12:14:00 A role for MORC2 in regulating DNA damage-induced G2 checkpoint through NAT10-mediated acetylation. 32112098

名称对应

Type IDs
Synonymous CMT2Z, ZCW3, ZCWCC1
Gene
UniProtKB-ID: MORC2_HUMAN
UniprotKB: Q9Y6X9
UniParc: UPI000041AB7E, UPI000012DB74
EMBL: BC019257, CH471095, CR456469, BC136782, AB020659, AL133637, AC004542
Ensembl: ENSG00000133422
KO: hsa:22880
Nucleutide sequences
EMBL-CDS: CAB63760.1, CAG30355.1, AAI36783.1, AAH19257.3, AAC12954.1, BAA74875.2, EAW59921.1
Ensembl_TRS: ENST00000215862, ENST00000397641
Protein sequencees
Ensembl_PRO: ENSP00000215862, ENSP00000380763
RefSeq: NP_001290185.1, NP_055756.1, XP_016884156.1, NP_001290186.1, XP_011528306.1
Others
UniRef100: UniRef100_Q9Y6X9
UniRef90: UniRef90_Q9Y6X9
UniRef50: UniRef50_Q9Y6X9
UniGene: Hs.555918
CCDS: CCDS33636.1, CCDS77668.1

全选

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