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9997 SCO2

9997

SCO2

SCO cytochrome c oxidase assembly protein 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition SCO cytochrome c oxidase assembly protein 2

研究结论

Date Results Publications
2020-12-12 13:23:00 Systemic Mitochondrial Protein Levels Correlate with Neuroimaging Measures in Chronically HIV-Infected Individuals. 31617381
2019-04-13 10:18:00 High expression of synthesis of cytochrome c oxidase 2 and TP53-induced glycolysis and apoptosis regulator can predict poor prognosis in human lung adenocarcinoma 29634976
2017-03-25 12:41:00 We identified one novel possibility of an extreme myopia-causing mutation in SCO2. No other disease-causing mutation was found in 101 extremely myopic Japanese patients, suggesting that SCO2 plays a limited role in Japanese extreme myopia. 27052445
2017-03-25 11:14:00 In gastric cancer, the expression of SCO2 and COX were not shown to be associated with the regulatory role of p53, unlike TIGAR expression. Nevertheless, a significantly high recurrence rate was found in a patient group with high COX expression 27499152
2017-01-14 11:17:00 oxidative stress-induced glycolysis-to-OXPHOS switch is mediated by synthesis of cytochrome c oxidase 2 (SCO2). These findings demonstrate p53-mediated OXPHOS function as a compensatory alteration in Fanconi anemia (FA)hematopoietic stem cells to ensure a functional but mildly impaired energy metabolism and suggest a cautious approach to manipulating p53 signaling in FA. 26676373

名称对应

Type IDs
Synonymous CEMCOX1, ECGF1, Gliostatin, MYP6, PD-ECGF, SCO1L, TP, TYMP, TdRPase
Gene
UniProtKB-ID: SCO2_HUMAN
UniprotKB: O43819
UniParc: UPI000013566C
EMBL: AF177385, AL021683, CR456569, BC102025, BC102024
Ensembl: ENSG00000284194
KO: hsa:9997
Nucleutide sequences
EMBL-CDS: CAG30455.1, AAI02026.1, AAI02025.1, CAA16671.1, AAF05313.1
Ensembl_TRS: ENST00000535425, ENST00000543927, ENST00000252785, ENST00000395693
Protein sequencees
Ensembl_PRO: ENSP00000379046, ENSP00000444433, ENSP00000252785, ENSP00000444242
RefSeq: NP_001162582.1, NP_001162581.1, NP_001162580.1, NP_005129.2
Others
UniRef100: UniRef100_O43819
UniRef90: UniRef90_O43819
UniRef50: UniRef50_O43819
UniGene: Hs.180903, Hs.730607
CCDS: CCDS14095.1

全选

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