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99929 Tiparp

99929

Tiparp

TCDD-inducible poly(ADP-ribose) polymerase

protein-coding

Mus musculus

基因描述

Type Description
Definition TCDD-inducible poly(ADP-ribose) polymerase

研究结论

Date Results Publications
2020-06-27 11:19:00 coronaviruses elicit AhR activation by an IDO1-independent pathway, contributing to upregulation of downstream effectors, including the proviral factor and to modulation of cytokine gene expression. 31694960
2020-06-06 10:05:00 Loss of Tiparp resulted in an aberrant organization of the mouse cortex, where the upper layers presented increased cell density in the knock-out mice compared with wild type. Tiparp loss predominantly affected the correct distribution and number of GABAergic neurons. Furthermore, neural stem cell proliferation was significantly reduced. Neural stem cells derived from Tiparp(-/-) mice showed a slower rate of migration. 31704703
2019-10-12 10:30:00 circHECTD1 functions as an endogenous MIR142 (microRNA 142) sponge to inhibit MIR142 activity, resulting in the inhibition of (TCDD inducible poly[ADP-ribose] polymerase) expression with subsequent inhibition of astrocyte activation via macroautophagy/autophagy. 29938598
2019-09-07 11:44:00 Tiparp(-/-) mice have increased sensitivity to 3-methylcholanthrene-induced liver toxicity. 31083300
2017-06-03 10:20:00 this study shows that aryl hydrocarbon receptor upregulates expression of which in turn causes downregulation of the IFN type I response 27089381

名称对应

Type IDs
Synonymous ARTD14, AW558171, PARP7
Gene
UniProtKB-ID: PARPT_MOUSE
UniprotKB: Q8C1B2
UniParc: UPI00000EA1E4
EMBL: AK150248, AK032453, AK028529, AK162094, BC068173
Ensembl: ENSMUSG00000034640
KO: mmu:99929
Nucleutide sequences
EMBL-CDS: AAH68173.1, BAC25994.1, BAC27876.1, BAE36720.1, BAE29412.1
Ensembl_TRS: ENSMUST00000047906
Protein sequencees
Ensembl_PRO: ENSMUSP00000048051
RefSeq: NP_849223.2
Others
UniRef100: UniRef100_Q8C1B2
UniRef90: UniRef90_Q8C1B2
UniRef50: UniRef50_Q7Z3E1
UniGene: Mm.246398
CCDS: CCDS17388.1

全选

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研究热度

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