| Type | Description |
|---|---|
| Definition | polypyrimidine tract binding protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 12:01:00 | PTBP3 appears to be a novel oncogene of CRC through binding to the IRES region of HIF-1alpha mRNA, which regulates HIF-1alpha translation. PTBP3 can serve as a promising predictive biomarker for recurrence and prognosis in patients with CRC. | 31291975 |
| 2019-11-09 12:41:00 | findings provide experimental evidence that PTBP3 may function as a metastatic gene in gastric cancer by regulating CAV1 through alternative splicing. | 29752441 |
| 2019-09-07 10:38:00 | ROD1 directly interacts with AID, which jointly bind bidirectionally transcribed RNAs to facilitate genome-wide AID targeting to Ig and non-Ig loci, suggesting that cooperative binding of the ROD1-AID complex on RNA provides the targeting specificity for AID. | 30143796 |
| 2019-08-24 11:17:00 | The Meg3-dependent association of PTBP3 with the promoters of p53 target genes suggests that Meg3 and PTBP3 restrain p53 activation. Our studies reveal a novel role of Meg3 and PTBP3 in regulating p53 signaling and endothelial function, which may serve as novel targets for therapies to restore endothelial homeostasis. | 30476192 |
| 2019-06-01 12:48:00 | the methylation profile combination of HKR1, ROD1, and NLRC5 could be a promising biomarker for aging in Hainan centenarians | 29394898 |
| Type | IDs |
|---|---|
| Synonymous | ROD1 |
| Gene |
UniProtKB-ID:
PTBP3_HUMAN,
A0A024R163_HUMAN
UniprotKB:
O95758,
A0A024R163
UniParc:
UPI000185D578,
UPI000000DA96,
UPI00004251C9,
UPI000041A12E,
UPI000046FDF8,
UPI0000071191,
UPI000021161D
EMBL:
AK001685,
BC039896,
BI463123,
AL158824,
AK302558,
BC044585,
CH471105,
CR749471,
AB023967,
AL359073
Ensembl:
ENSG00000119314
KO:
hsa:9991
|
| Nucleutide sequences |
EMBL-CDS:
EAW59100.1,
AAH44585.1,
CAH18301.1,
AAH39896.1,
BAG50959.1,
BAG63824.1,
BAA75466.1,
EAW59101.1
Gene_ORFName:
hCG_1996226
Ensembl_TRS:
ENST00000374255,
ENST00000458258,
ENST00000374257,
ENST00000334318,
ENST00000343327
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363373,
ENSP00000414921,
ENSP00000363375,
ENSP00000334499,
ENSP00000340705
RefSeq:
NP_001157262.1,
NP_001362849.1,
XP_011517567.1,
NP_001231827.1,
NP_001157260.1,
NP_001362847.1,
NP_001231826.1,
NP_001231825.1,
NP_005147.3,
XP_024303490.1
|
| Others |
UniRef100:
UniRef100_O95758
UniRef90:
UniRef90_O95758
UniRef50:
UniRef50_O95758
UniGene:
Hs.269988
CCDS:
CCDS59140.1,
CCDS6784.1,
CCDS59141.1,
CCDS55332.1,
CCDS55333.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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