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99890 Prmt6

99890

Prmt6

protein arginine N-methyltransferase 6

protein-coding

Mus musculus

基因描述

Type Description
Definition protein arginine N-methyltransferase 6

研究结论

Date Results Publications
2021-03-20 13:32:00 Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6. 33008887
2020-08-29 12:43:00 The methyltransferase PRMT6 attenuates antiviral innate immunity by blocking TBK1-IRF3 signaling. 29973649
2019-09-28 11:59:00 Loss of PPARalpha from the intestine promotes colon carcinogenesis by increasing DNMT1/PRMT6-mediated DNA methylation. 31154022
2019-08-24 12:14:00 It was confirmed that PRMT6 was involved in the process of adipocyte differentiation. In addition, PRMT6 interacted with, but did not methylate, PPARgamma. PRMT6 bound to the PPARresponsive regulatory element of the adipocyte Protein 2 (aP2) promoter in conjunction with PPARgamma and generated the repressive epigenetic mark arginine 2 on histone H3 asymmetric dimethylation, which suppressed aP2 gene expression. 30942395
2016-05-28 10:50:00 Six crystal structures of PRMT6 from Mus musculus, solved and refined at 1.34 A for the highest resolution structure are described. 26094878

名称对应

Type IDs
Synonymous AW124876, BB233495, Hrmt1l6
Gene
UniProtKB-ID: ANM6_MOUSE
UniprotKB: Q6NZB1
UniParc: UPI000002885C
EMBL: AK172105, AK172003, AK172722, BC022899, BC066221, AK087551, AK034732
Ensembl: ENSMUSG00000049300
KO: mmu:99890
Nucleutide sequences
EMBL-CDS: AAH22899.1, AAH66221.1, BAC39923.1, BAE43144.1, BAC28811.1, BAE42769.1, BAE42828.1
Ensembl_TRS: ENSMUST00000190378, ENSMUST00000106567, ENSMUST00000168412
Protein sequencees
Ensembl_PRO: ENSMUSP00000140836, ENSMUSP00000129801, ENSMUSP00000102177
RefSeq: NP_849222.3
Others
UniRef100: UniRef100_Q6NZB1
UniRef90: UniRef90_Q6NZB1
UniRef50: UniRef50_Q96LA8
UniGene: Mm.36115, Mm.393526
CCDS: CCDS38605.1

全选

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