| Type | Description |
|---|---|
| Definition | protein phosphatase 4 regulatory subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:14:00 | PP4R1 interacts with HMGA2 to promote non-small-cell lung cancer migration and metastasis via activating MAPK/ERK-induced epithelial-mesenchymal transition. | 32077156 |
| 2018-04-14 12:03:00 | Data identify PP4R1 as a novel target for virus subversion of the host anti-viral response. | 28445980 |
| 2015-08-08 11:14:00 | PP4R1 could mediate the dephosphorylation of TRAF2 Ser11. | 25134449 |
| 2012-12-29 11:40:00 | PP4R1 expression was triggered upon activation and proliferation of primary human T lymphocytes and deficiency for PP4R1 caused sustained and increased IKK activity, T cell hyperactivation, and aberrant NF-kappaB signaling in NF-kappaB-addicted T cell lymphomas | 23084358 |
| 2010-06-30 22:04:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | MEG1, PP4(Rmeg), PP4R1 |
| Gene |
UniProtKB-ID:
PP4R1_HUMAN
UniprotKB:
Q8TF05
UniParc:
UPI000006D6DE,
UPI0000073D56
EMBL:
BC060829,
AF100744,
AF200478,
U79267,
AP000902,
AP001381,
AF111106
Ensembl:
ENSG00000154845
KO:
hsa:9989
|
| Nucleutide sequences |
EMBL-CDS:
AAB50211.1,
AAD09818.1,
AAL78298.1,
AAD43008.1,
AAH60829.1
Ensembl_TRS:
ENST00000400556,
ENST00000400555
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383401,
ENSP00000383402
RefSeq:
NP_005125.1,
NP_001369491.1,
XP_011524077.1,
XP_016881596.1,
XP_011524078.1,
NP_001035847.1,
XP_016881594.1,
XP_011524081.1
|
| Others |
UniRef100:
UniRef100_Q8TF05
UniRef90:
UniRef90_Q8TF05
UniRef50:
UniRef50_Q8TF05
UniGene:
Hs.743236
CCDS:
CCDS42412.1,
CCDS42413.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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