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9972 NUP153

9972

NUP153

nucleoporin 153

protein-coding

Homo sapiens

基因描述

Type Description
Definition nucleoporin 153

研究结论

Date Results Publications
2020-12-05 13:03:00 Viral protein X unlocks the nuclear pore complex through a human Nup153-dependent pathway to promote nuclear translocation of the lentiviral genome. 31913756
2019-12-07 10:53:00 Seh1 is not required for the association of the Nup107 complex with mitotic chromosomes, but it is essential for the association of both the GATOR2 complex and nucleoporin Nup153 with mitotic chromosomes. 29618633
2019-06-01 11:09:00 Nup153 effectively assembled Nup98, Nup62 and Pom121 of the nuclear pore complex at the end of the mitosis. 30821042
2018-09-22 10:37:00 Nup153 is essential for the HIV-1 nuclear import in nondividing cells, and CPSF6 is important for HIV-1 integration. 29997211
2018-09-15 12:13:00 Despite the requirement of all three nucleoporins for accurate NHEJ, only Nup153 is needed for proper nuclear import of 53BP1 and SENP1-dependent sumoylation of 53BP1. Our data support the role of Nup153 as an important regulator of 53BP1 activity and efficient NHEJ. 28576968

名称对应

Type IDs
Synonymous HNUP153, N153
Gene
UniProtKB-ID: NU153_HUMAN
UniprotKB: P49790
UniParc: UPI0001AE7240, UPI000013D251, UPI0000E09D94
EMBL: AK295644, AL157776, AB210024, BC052965, AL138824, Z25535, AL138724
Ensembl: ENSG00000124789
KO: hsa:9972
Nucleutide sequences
EMBL-CDS: BAG58514.1, BAE06106.1, CAA80982.1, AAH52965.1
Ensembl_TRS: ENST00000537253, ENST00000613258, ENST00000262077
Protein sequencees
Ensembl_PRO: ENSP00000444029, ENSP00000478627, ENSP00000262077
RefSeq: XP_006715354.1, XP_006715353.1, XP_005249564.1, NP_001265138.1, NP_001265139.1, XP_011513330.1, NP_005115.2, XP_016867083.1
Others
UniRef100: UniRef100_P49790
UniRef90: UniRef90_P49790
UniRef50: UniRef50_P49790
UniGene: Hs.601591
CCDS: CCDS64359.1, CCDS75407.1, CCDS4541.1

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