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9962 SLC23A2

9962

SLC23A2

solute carrier family 23 member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 23 member 2

研究结论

Date Results Publications
2021-02-13 13:20:00 PHLPP2 is a novel biomarker and epigenetic target for the treatment of vitamin C in pancreatic cancer. 32319585
2020-05-23 13:17:00 Augmented expression of an SVCT2 mitochondrial form appears to be a common hallmark across all human cancers and might have implications in cancer cells survival capacity against pro-oxidant environments 30902760
2019-06-29 12:17:00 We propose that two mechanisms of modulation of SVCT2 levels at the plasma membrane, one at the early secretory pathway and another at the endocytic compartments, have key protective implications in the homeostasis of metabolically active and specialized tissues. 29545069
2017-12-30 12:15:00 enhanced expression of the high affinity ascorbic acid transporter SVCT2, which tightly regulates intracellular ascorbic acid concentrations. 26646539
2017-12-23 12:36:00 mutant KRAS can be bypassed by L-ascorbic acid in an SVCT-2-dependent manner. Furthermore, SVCT-2 in mutant KRAS colon cancer may act as a potent marker for potentiating L-ascorbic acid co-treatment with cetuximab. 27012422

名称对应

Type IDs
Synonymous NBTL1, SLC23A1, SVCT2, YSPL2
Gene
UniProtKB-ID: S23A2_HUMAN, A0A140VK48_HUMAN
UniprotKB: Q9UGH3, A0A140VK48
UniParc: UPI0000D61026, UPI0000136292
EMBL: AF058319, AK296304, AJ269478, CH471133, AJ292318, AL389886, AF092511, D87075, AL121890, BC013112, AL109841, AF164142, AY380556, HM005588
Ensembl: ENSG00000089057
KO: hsa:9962
Nucleutide sequences
EMBL-CDS: AAH13112.1, BAG59003.1, CAC83100.1, AAC78806.1, AAQ79775.1, AAF80493.1, CAB58120.1, BAA13244.2, AAD11783.1, AEE61185.1, EAX10439.1
Gene_ORFName: hCG_2020216
Ensembl_TRS: ENST00000379333, ENST00000338244
Protein sequencees
Ensembl_PRO: ENSP00000368637, ENSP00000344322
RefSeq: NP_005107.4, NP_976072.1
Others
UniRef100: UniRef100_Q9UGH3
UniRef90: UniRef90_Q9UGH3
UniRef50: UniRef50_Q9UGH3
UniGene: Hs.516866
CCDS: CCDS13085.1

全选

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