Type | Description |
---|---|
Definition | ubiquitin specific peptidase 15 |
Date | Results | Publications |
---|---|---|
2021-03-20 13:24:00 | TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. | 32101751 |
2020-06-20 12:25:00 | modifications of USP15 and USP4 by phosphorylation are important for the regulation of their localization required for cellular function in the spliceosome. | 31330151 |
2020-02-29 10:07:00 | The molecular structure of USP15 and its ubiquitin variant inhibitors has been reported. | 30713027 |
2019-11-23 12:33:00 | USP15 participates in HCV propagation in hepatic cells. | 30626683 |
2019-04-13 11:58:00 | Study reports that USP15 affects cancer cell response to inhibitors by regulating homologous recombination repair. USP15 is recruited to DNA double-strand breaks (DSBs) by MDC1. USP15 deubiquitinates BARD1 BRCT domain, and promotes BARD1-HP1gamma interaction, resulting in BRCA1/BARD1 retention at DSBs. Cancer-associated USP15 mutations, with decreased USP15-BARD1 interaction, increases Pduanyu37 inhibitor sensitivity. | 30874560 |
Type | IDs |
---|---|
Synonymous | UNPH-2, UNPH4 |
Gene |
UniProtKB-ID:
UBP15_HUMAN
UniprotKB:
Q9Y4E8
UniParc:
UPI000002B67D,
UPI000002B67C,
UPI00001379F8,
UPI000006EC4F
EMBL:
BC020688,
AB011101,
AF153604,
AC079035,
AC048342,
AK023703,
AF106069,
AK292337,
BC125123,
BC063454,
AC117370,
AF013990
Ensembl:
ENSG00000135655
KO:
hsa:9958
|
Nucleutide sequences |
EMBL-CDS:
AAD52099.1,
AAH20688.1,
AAG28973.1,
AAH63454.1,
BAA25455.2,
AAD41086.1,
BAF85026.1,
BAB14648.1,
AAI25124.1
Ensembl_TRS:
ENST00000280377,
ENST00000353364,
ENST00000312635
|
Protein sequencees |
Ensembl_PRO:
ENSP00000258123,
ENSP00000309240,
ENSP00000280377
RefSeq:
NP_001338092.1,
NP_001338090.1,
NP_001239008.1,
NP_001239007.1,
NP_001338094.1,
NP_001338088.1,
NP_001338095.1,
NP_001338089.1,
NP_006304.1,
NP_001338091.1,
NP_001338093.1
|
Others |
UniRef100:
UniRef100_Q9Y4E8
UniRef90:
UniRef90_Q9Y4E8
UniRef50:
UniRef50_Q9Y4E8
UniGene:
Hs.434951
CCDS:
CCDS58250.1,
CCDS58251.1,
CCDS8963.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员