Type | Description |
---|---|
Definition | cell division cycle 25C |
Date | Results | Publications |
---|---|---|
2021-02-06 13:53:00 | Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells. | 32393310 |
2020-05-02 12:02:00 | Studied p38MAPK-ERK-JNK-cell division cycle 25C (CDC25C) expression in polyploid giant cancer cells and clinicopathological significance of p38MAPK, ERK, JNK, and CDC25C expression in human ovarian and breast cancers. | 31734829 |
2019-11-16 11:46:00 | Increased expression of CDC25B or CDC25C are mechanisms by which skin cancers evade apoptotic cell death. | 31237025 |
2019-01-12 11:38:00 | AMPK directly phosphorylates CDC25C on serine 216, a well-conserved inhibitory phosphorylation event, which has been shown to mediate DNA damage-induced G2-phase arrest. The acute induction of CDC25C or suppression of WEE1 partially restores mitosis entry in the context of AMPK activation. | 29467227 |
2018-12-29 12:15:00 | Cells lacking ARID1A show enhanced AURKA transcription, which leads to the persistent activation of CDC25C, a key protein for G2/M transition and mitotic entry. | 30097580 |
Type | IDs |
---|---|
Synonymous | CDC25, PPP1R60 |
Gene |
UniProtKB-ID:
MPIP3_HUMAN,
B4DX61_HUMAN
UniprotKB:
P30307,
B4DX61
UniParc:
UPI00017A8316,
UPI000020C6C6,
UPI000013E3D2,
UPI000002AE3E,
UPI000002AE3F
EMBL:
AF277725,
AY497474,
AF277723,
AJ304504,
AF277726,
AF312681,
AK301828,
M34065,
CH471062,
BC019089
Ensembl:
ENSG00000158402
KO:
hsa:995
|
Nucleutide sequences |
EMBL-CDS:
EAW62149.1,
AAL26835.1,
AAG41888.1,
AAG41887.1,
CAC19192.1,
AAG41885.1,
EAW62145.1,
AAR32098.1,
AAH19089.1,
AAA35666.1,
BAG63273.1
Ensembl_TRS:
ENST00000415130,
ENST00000348983,
ENST00000513970,
ENST00000514555,
ENST00000323760
|
Protein sequencees |
Ensembl_PRO:
ENSP00000392631,
ENSP00000321656,
ENSP00000424795,
ENSP00000425470,
ENSP00000345205
RefSeq:
NP_001350956.1,
XP_011542061.1,
NP_001305027.1,
NP_001350955.1,
NP_073720.1,
XP_005272202.1,
XP_011542065.1,
NP_001274511.1,
NP_001781.2,
NP_001350957.1,
XP_011542064.1,
XP_011542063.1,
XP_006714802.1,
NP_001274512.1,
XP_011542066.1,
XP_011542062.1
|
Others |
UniRef100:
UniRef100_P30307,
UniRef100_B4DX61
UniRef90:
UniRef90_P30307
UniRef50:
UniRef50_P30307
UniGene:
Hs.656
CCDS:
CCDS4203.1,
CCDS4202.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员