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995 CDC25C

995

CDC25C

cell division cycle 25C

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell division cycle 25C

研究结论

Date Results Publications
2021-02-06 13:53:00 Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells. 32393310
2020-05-02 12:02:00 Studied p38MAPK-ERK-JNK-cell division cycle 25C (CDC25C) expression in polyploid giant cancer cells and clinicopathological significance of p38MAPK, ERK, JNK, and CDC25C expression in human ovarian and breast cancers. 31734829
2019-11-16 11:46:00 Increased expression of CDC25B or CDC25C are mechanisms by which skin cancers evade apoptotic cell death. 31237025
2019-01-12 11:38:00 AMPK directly phosphorylates CDC25C on serine 216, a well-conserved inhibitory phosphorylation event, which has been shown to mediate DNA damage-induced G2-phase arrest. The acute induction of CDC25C or suppression of WEE1 partially restores mitosis entry in the context of AMPK activation. 29467227
2018-12-29 12:15:00 Cells lacking ARID1A show enhanced AURKA transcription, which leads to the persistent activation of CDC25C, a key protein for G2/M transition and mitotic entry. 30097580

名称对应

Type IDs
Synonymous CDC25, PPP1R60
Gene
UniProtKB-ID: MPIP3_HUMAN, B4DX61_HUMAN
UniprotKB: P30307, B4DX61
UniParc: UPI00017A8316, UPI000020C6C6, UPI000013E3D2, UPI000002AE3E, UPI000002AE3F
EMBL: AF277725, AY497474, AF277723, AJ304504, AF277726, AF312681, AK301828, M34065, CH471062, BC019089
Ensembl: ENSG00000158402
KO: hsa:995
Nucleutide sequences
EMBL-CDS: EAW62149.1, AAL26835.1, AAG41888.1, AAG41887.1, CAC19192.1, AAG41885.1, EAW62145.1, AAR32098.1, AAH19089.1, AAA35666.1, BAG63273.1
Ensembl_TRS: ENST00000415130, ENST00000348983, ENST00000513970, ENST00000514555, ENST00000323760
Protein sequencees
Ensembl_PRO: ENSP00000392631, ENSP00000321656, ENSP00000424795, ENSP00000425470, ENSP00000345205
RefSeq: NP_001350956.1, XP_011542061.1, NP_001305027.1, NP_001350955.1, NP_073720.1, XP_005272202.1, XP_011542065.1, NP_001274511.1, NP_001781.2, NP_001350957.1, XP_011542064.1, XP_011542063.1, XP_006714802.1, NP_001274512.1, XP_011542066.1, XP_011542062.1
Others
UniRef100: UniRef100_P30307, UniRef100_B4DX61
UniRef90: UniRef90_P30307
UniRef50: UniRef50_P30307
UniGene: Hs.656
CCDS: CCDS4203.1, CCDS4202.1

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