| Type | Description |
|---|---|
| Definition | glutamine-fructose-6-phosphate transaminase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 11:38:00 | Glutamine-fructose-6-phosphate transaminase 2 (GFPT2) activates the hexosamine biosynthetic pathway to increase the nuclear location of beta-catenin and promote epithelial-mesenchymal transformation of serous ovarian cancer. | 31685298 |
| 2019-08-17 12:54:00 | Elevated GFPT2 expression correlates with poor clinical outcome in non-small cell lung cancer. | 30885209 |
| 2019-08-10 11:02:00 | Transcriptome analysis of human primary non-small cell lung cancer specimens showed that glucose uptake associated with GFPT2-expressing cancer-associated fibroblasts was prognostic for adenocarcinoma. GFPT2 was predictive of glucose uptake independent of GLUT1, the primary glucose transporter, and was prognostically significant at both gene and protein level. | 29760045 |
| 2019-04-20 11:24:00 | Homozygosity of the GFPT2 p.Arg366Gln mutation was associated with increased levels of reactive oxygen species in spermatozoa and decreased sperm motility. | 30849544 |
| 2019-03-09 10:51:00 | PPP2R2A interacts with GFPT1/2, and leads to the phosphorylation of GFPT2, which can regulate the cellular O-GlcNAcylation in breast cancer | 29943541 |
| Type | IDs |
|---|---|
| Synonymous | GFAT, GFAT 2, GFAT2 |
| Gene |
UniProtKB-ID:
GFPT2_HUMAN,
B3KMR8_HUMAN,
A0A0S2Z4X9_HUMAN
UniprotKB:
O94808,
B3KMR8,
A0A0S2Z4X9
UniParc:
UPI000014F5AC,
UPI000015F48B
EMBL:
AK022507,
KU178494,
AB016789,
BT009818,
CH471165,
BC000012
Ensembl:
ENSG00000131459
KO:
hsa:9945
|
| Nucleutide sequences |
EMBL-CDS:
AAH00012.1,
AAP88820.1,
BAA74731.1,
BAG51080.1,
ALQ33952.1,
EAW53756.1
Gene_ORFName:
hCG_15277
Ensembl_TRS:
ENST00000253778
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000253778
RefSeq:
NP_005101.1
|
| Others |
UniRef100:
UniRef100_O94808,
UniRef100_B3KMR8
UniRef90:
UniRef90_O94808
UniRef50:
UniRef50_Q06210
UniGene:
Hs.696497
CCDS:
CCDS43411.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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