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994 CDC25B

994

CDC25B

cell division cycle 25B

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell division cycle 25B

研究结论

Date Results Publications
2021-02-02 13:24:00 CDC25B is associated with the risk of hepatocellular carcinoma, but not related to persistent infection of hepatitis B virus in a Chinese population. 32248384
2020-08-22 15:30:00 Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression. 30718768
2019-11-16 11:46:00 Increased expression of CDC25B or CDC25C are mechanisms by which skin cancers evade apoptotic cell death. 31237025
2019-08-17 10:08:00 Depletion of TIAR accelerates mitotic entry and leads to chromosomal instability in response to replication stress, in a manner that can be alleviated by the concomitant depletion of Cdc25B or inhibition of CDK1. Since TIAR retains CDK1 in GMGs and attenuates CDK1 activity, we propose that the assembly of GMGs may represent a so far unrecognized mechanism that contributes to the activation of the G2/M checkpoint 30538118
2019-01-12 12:29:00 These findings indicate that CDC25B facilitates the dephosphorylation of nucleoprotein (NP), which is vital for regulating NP functions and the life cycle of influenza a virus. 30240957

名称对应

Type IDs
Gene
UniProtKB-ID: MPIP2_HUMAN, G8JLH2_HUMAN, B4DQZ3_HUMAN, B4DRC3_HUMAN, B3KS38_HUMAN, Q6MZW8_HUMAN, B4DIG0_HUMAN, E1YMX4_HUMAN
UniprotKB: P30305, G8JLH2, B4DQZ3, B4DRC3, B3KS38, Q6MZW8, B4DIG0, E1YMX4
UniParc: UPI00020654EE, UPI000012F474, UPI000013CBC5, UPI000035E2C7, UPI0001E5E812, UPI0000E06405, UPI0000206946, UPI0000440985, UPI00017A7C52, UPI000002AE3C, UPI000002AE3B
EMBL: AF036233, AK295573, BX640836, AY494082, Z68092, AK092713, S78187, CH471133, M81934, AK299028, BC006395, FR695901, X96436, BC009953, AK299192, AL109804, FR695900, BC051711
Ensembl: ENSG00000101224
KO: hsa:994
Nucleutide sequences
EMBL-CDS: AAH51711.1, EAX10498.1, EAX10496.1, AAR26469.1, AAB94624.1, AAB21139.1, EAX10493.1, EAX10491.1, AAH09953.1, EAX10492.1, CAA65303.1, EAX10497.1, AAB94622.1, EAX10494.1, AAA58416.1, EAX10499.1, CAA92108.1, AAH06395.1, BAG61105.1, BAG61235.1, EAX10500.1, EAX10501.1, CBX26628.1, BAG52600.1, CAE45909.2, BAG58472.1, CBX26629.1
Gene_ORFName: hCG_39252
Ensembl_TRS: ENST00000245960, ENST00000439880, ENST00000340833, ENST00000379598, ENST00000344256
Protein sequencees
Ensembl_PRO: ENSP00000405972, ENSP00000245960, ENSP00000339170, ENSP00000368918, ENSP00000339125
RefSeq: NP_001274448.1, NP_068658.1, NP_001274445.1, NP_001274447.1, NP_004349.1, NP_001274446.1, NP_001274451.1, NP_068659.1, NP_001274453.1, NP_001274449.1
Others
UniRef100: UniRef100_G8JLH2, UniRef100_E1YMX4, UniRef100_B4DQZ3, UniRef100_Q6MZW8, UniRef100_B4DIG0, UniRef100_P30305, UniRef100_B4DRC3
UniRef90: UniRef90_P30305-2, UniRef90_Q6MZW8, UniRef90_P30305, UniRef90_F7FDW6
UniRef50: UniRef50_P30305, UniRef50_P30305-2, UniRef50_A0A3Q2U9H7
UniGene: Hs.153752
CCDS: CCDS13067.1, CCDS13065.1, CCDS13066.1

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